College of Minnesota Researchers Create a Better 3D-Printed Organ Model

3D-printed organ designs include proven lots of promise in medicine by supplying doctors having a tangible representation of the organ being studied. While these models are wonderful at mimicking the dimensions and exterior appearance of the biological counterparts, otherwise they’re typically not so helpful.

Researchers in the College of Minnesota have finally developed 3D-printed organ mixers are a little more functional. Furthermore they precisely replicate the look of a body organ, they also precisely mimic both exterior and internal physiological structures, mechanical qualities, and feel. It was accomplished by developing customized silicone-based inks that precisely match the mechanical qualities from the biological tissues being mimicked after which fabricating the organ models on custom-built 3D printers.

They also attached flexible, 3D-printed sensors towards the organ mixers measure pressure and pressure. This enables researchers and clinicians to see the results of compression tests and the use of sutures along with other surgical tools around the model, that could better train surgeons about how much pressure they are able to apply with no damage to tissues.

Researchers will also be investigating how you can print with multiple inks to produce more complicated organ models. Such models may even mimic the existence of a tumor or deformity, so surgeons can test different techniques for removing tumors or correcting physiological complications.

Check out a short video explaining the organ models:

Study in Advanced Materials Technologies: 3D Printed Organ Models with Physical Qualities of Tissue and Integrated Sensors…

Via: College of Minnesota…

(hat tip: MDO)

Scott Jung

Scott Jung (@scottjung) is really a Plastic Valley-based health and medical technology journalist and advocate. He is a guest cause of Intel’s iQ e-magazine and Rock Health’s corporate blog and it has provided live, on-site coverage from the Worldwide CES and Digital Health Summit, TEDMED, and Stanford Medicine X conference for Medgadget. Most lately, he’s been appearing on’s The Brand New Screen Savers like a semi-regular health and medical technology correspondent. Scott holds a b -.Utes. degree in Biomedical Engineering in the College of Los Angeles. Scott is definitely searching for the following big factor in medical technology and digital health. Thinking about helping him transform lives? Make contact with him at http://scottjung.internet

Food and drug administration digital health draft guidance scales back regulating certain kinds of software

data, patient, medical records, health data, healthcare data

The U.S. Fda released draft assistance with digital health rules made to reduce ambiguity over the sorts of clinical decision support tools and patient decision support tools that must be reviewed through the Food and drug administration and individuals that didn’t.  The regulator also issued final assistance with standardizing the way in which safety, effectiveness and gratifaction are assessed for Software like a Medical Device. But Bradley Merrill Thompson, general counsel for that industry group Clinical Decision Support Coalition, speaking for themself, stated he was disappointed by a few of the proposals that the coalition have been waiting on for many years.

CDSC has labored to build up an offer for the way to attract the road between controlled and unregulated clinical decision support software.

Reducing the kinds of software programs that require Food and drug administration clearance would free up the regulator to concentrate its attention on technologies it regards like a greater priority. The FDA offered a couple of examples in the draft guidance documents of the items would and wouldn’t require its approval.


  • Software that manipulates or analyzes images along with other data acquired from the radiological device, like a CT imaging device, to produce 3D types of the location intended to be utilized in planning memory foam/dental surgery having a device still requires Food and drug administration clearance.
  • Software that can help to recognize drug-drug interaction and drug-allergy
    contraindication alerts, according to Food and drug administration-approved drug labeling and patient-specific information, to avoid adverse drug occasions doesn’t require Food and drug administration clearance.
  • The Food and drug administration would still evaluate software used alongside home bloodstream testing needed with the utilization of anticoagulents for dosing adjustments in line with the outcome of the house bloodstream test with no patient seeking consultation using their doctor.

The Food and drug administration also shared an announcement by Commissioner Dr. Scott Gottlieb ready for a look and feel prior to the Senate HELP Committee hearing now.

“We believe our proposals for controlling [clinical decision support] and [patient decision support] not just match the provisions from the [21st] Cures Act, but additionally strike the best balance between making certain patient safety and promoting innovation.”

Regardless of the intention behind the brand new draft guidance, Thompson, part of law practice Epstein Becker Eco-friendly in Washington D.C., expressed disappointment with a few areas of the draft guidance. The clinical decision support guidance have been six years within the making however in an emailed statement about Food and drug administration Commissioner Scott Gottlieb’s comments, he stated he couldn’t praise it.

He noted:

The issue is that FDA seems to possess walked from creating a risk-based determination.

Main issue, clinical decision support software programs are software that can take some form of medical understanding and applies it for an individual patient to create a person recommendation. According to that, people acquainted with healthcare can most likely readily visit a wide spectrum of risk connected with your software.

In the dangerous finish, there’s software which makes essential and direct strategies for specific chemotherapy treatment according to a multitude of data.  And when that software helps make the wrong recommendation, it is extremely possible the individual would suffer, even die.

Also, he shared what he’d wished the Food and drug administration would do:

“What I believe a lot of us in [the] industry were wishing for was an attempt by Food and drug administration to distinguish high from safe like a grounds for regulation. We didn’t have that. Worse, it seems in line with the guidance that Food and drug administration is uninterested in drawing that line.”

Also, he expressed alarm using the FDA’s conclusion on clinical decision support helped by machine learning, noting the Food and drug administration didn’t appear to possess any plans for differentiating between how miracle traffic bot is controlled according to risk.

Photo: nevarpp, Getty Images

MedCity ENGAGE, October 23-24 in North Park, concentrates on the most recent strategies and innovations to boost patient engagement, care delivery and company wellness. Use code MCNTAG in order to save $50.

Novel Transforming Glue Treats Emergency Battlefield Eye Injuries

Statistically, war-related eye injuries have continuously elevated from a part of a percent up to ten to fifteen percent previously couple of decades. A number of these injuries result in permanent vision loss as a result of insufficient nearby medical facilities or even the proper tools to deal with them.

Researchers in the College of Los Angeles allow us a sophisticated material that medics can quickly deploy and that’s customized for various kinds of ocular trauma. Like superglue for that eyes. Initially developed being an adhesive for USC’s famous retinal implants, the glue, a hydrogel called PNIPAM, poly(N-isopropylacrylamide) has unique chemical qualities: when cooled, it might be a liquid for simple application, so when heated, it might be semi-solid with strong adhesive qualities. After a little modifications, they discovered that the hydrogel could form a good seal after being injected in to the eye and reaching the eye’s temperature. The operation is fully reversible simply by applying awesome water, which reverts the hydrogel back to a liquid condition for removal. Research on rabbit eyes demonstrated the hydrogel effectively improved intraocular pressures without inflammation or infection over four days.

Furthermore, they created a special portable syringe for that hydrogel. The syringe includes a cooling chamber filled with calcium ammonium nitrate crystals (those you discover in instant cold packs). Once the chamber is stuffed with water, the temperature from the syringe drops in under thirty seconds therefore the hydrogel becomes liquid and could be injected.

Anticipation would be that the special hydrogel/cooling syringe  combo is going to be utilized on the battlefields in addition to rural ER’s and mass casualty situations. Medics and first-responders can rapidly deploy the hydrogel to stabilize the individual until an ophthalmologist can repair the harm.

Journal abstract in Science Translational Medicine: A reversible thermoresponsive sealant for temporary closure of ocular trauma…

More information from USC: A brand new portable gel that may save an hurt eye…

Scott Jung

Scott Jung (@scottjung) is really a Plastic Valley-based health and medical technology journalist and advocate. He is a guest cause of Intel’s iQ e-magazine and Rock Health’s corporate blog and it has provided live, on-site coverage from the Worldwide CES and Digital Health Summit, TEDMED, and Stanford Medicine X conference for Medgadget. Most lately, he’s been appearing on’s The Brand New Screen Savers like a semi-regular health and medical technology correspondent. Scott holds a b -.Utes. degree in Biomedical Engineering in the College of Los Angeles. Scott is definitely searching for the following big factor in medical technology and digital health. Thinking about helping him transform lives? Make contact with him at http://scottjung.internet

Big ideas in AI, digital health, reimbursement to become addressed at 2018 MedCity INVEST

MedCity INVEST continues to be the main thing on discussing the large ideas in healthcare for a long time. No question greater than 400 attended in 2016.

The coming year isn’t any different.

Because the final diary for the conference on May 1-2 in Chicago shows, we are discussing these following topics of deep relevance to healthcare transformation: going past the hype in artificial intelligence to what’s practical exploring how startups may avoid dying with a 1000 pilots and just how reimbursement is surface of mind for investors and hospital buyers.

We’ve also announced the Pitch Perfect contest, and we’re inviting startups across all healthcare sectors — medical devices, diagnostics, biopharma, health IT and health services — to try to get an opportunity to be selected. Selected startups will show live to idol judges in the conference in the Four Seasons hotel throughout the conference.

We’re adding 2018 loudspeakers these days and that i aspire to help you within the Windy City.

MedCity ENGAGE, October 23-24 in North Park, concentrates on the most recent strategies and innovations to boost patient engagement, care delivery and company wellness. Use code MCNTAG in order to save $50.

Samsung Develops Application to permit Color Blind Proprietors to savor Their New TVs

New TVs were once more among the bestsellers throughout the Black Friday sales. But an believed 8 % of people that may have obtained a new TV now can’t fully enjoy its vibrant 4K Ultra HD, HDR, OLED, melt-your-eyeballs glory due to color blindness.

However, should you obtained a Samsung TV, you might be fortunate. Samsung, with the aid of Budapest College of Technology, is promoting an application known as SeeColors that can help color blind users assess their visual color spectrum and adjust the colour settings on their own TV accordingly to boost the image. The mobile application relies on a special digital diagnostic method produced by the college known as Colorlite Test, or C-Test. This process uses the idea of color filters and mathematical modeling to identify the kinds and amounts of color blindness.

The feature can be obtained for those Samsung QLED TV’s, and also the SeeColors application obtainable within the Google Play Store and Universe Application Store.

More information: Samsung Launches SeeColors Application for QLED TV to aid Individuals with Color Vision Deficiency (CVD)…

(hat tip: Engadget)

Scott Jung

Scott Jung (@scottjung) is really a Plastic Valley-based health and medical technology journalist and advocate. He is a guest cause of Intel’s iQ e-magazine and Rock Health’s corporate blog and it has provided live, on-site coverage from the Worldwide CES and Digital Health Summit, TEDMED, and Stanford Medicine X conference for Medgadget. Most lately, he’s been appearing on’s The Brand New Screen Savers like a semi-regular health and medical technology correspondent. Scott holds a b -.Utes. degree in Biomedical Engineering in the College of Los Angeles. Scott is definitely searching for the following big factor in medical technology and digital health. Thinking about helping him transform lives? Make contact with him at http://scottjung.internet

OSF Innovation pairs track of MassChallenge to assist healthcare startups

OSF Innovation, which belongs to Peoria, Illinois-based OSF HealthCare, has partnered with MassChallenge, an accelerator in Boston.

More particularly, OSF signed a yearlong agreement to become a sponsor of [email protected], that helps digital health entrepreneurs. This program is aimed toward startups which have elevated under $5 million and generate under $5 million in revenue.

PULSE is comparatively new. It launched last September, and three several weeks later, it revealed the very first cohort of companies. Thirty-one startups were selected from a swimming pool of 439 applicants. The participants vary wildly, concentrating on from cancer diagnostics to virtual reality.

By teaming track of the accelerator, OSF will get the opportunity to vet startups that put on participate the 2nd PULSE class. OSF may then select as much as two companies to mentor by initiating pilots,  presenting these to leaders and helping them find investment possibilities.

“We are searching for businesses focusing on technology, services and products which will solve an OSF need,” Stan Lynall, OSF Ventures’ v . p . of venture investments, stated inside a statement. “These include solutions for removing barriers to look after disadvantaged individuals, transforming how care is sent to seniors and expanding use of care with techniques we haven’t attempted before.”

This isn’t OSF HealthCare’s initial step in to the startup world. In April 2016, it launched its very own investment arm, OSF Ventures, which lately committed to PatientWisdom. The startup includes a digital platform that zeroes in on which truly matters to patients.

“Both PULSE and OSF Innovation be part of the fact that startups can dramatically improve healthcare and boost the lives of patients all over the world,Inches Nick Dougherty, PULSE’s program director, noted inside a statement. “We’re excited to become partnering using their team in 2018 to assist startups create prevalent impact.”

Based on a news release, 2010 [email protected] program is going to be centered on cybersecurity, genomics, the opioid epidemic and diet, amongst others topics.

The 2018 PULSE cohort is going to be unveiled on December 13, and also the six-month program will begin on The month of january 9.

Photo: Olivier Le Moal, Getty Images

First flushable pregnancy test will get pre-market approval from Food and drug administration

Pregnancy test by Lia Diagnostics

The U.S. Fda granted pre-market approval for Lia Diagnostics’ home pregnancy test recently. It marks the very first pregnancy test made from a biodegradeable paper that may be flushed lower a rest room.  The pre-market approval process is granted to Class 3 medical devices posted for scientific and regulatory review to judge safety and effectiveness.

Lia Diagnostics announced this news at TechCrunch Disrupt Berlin now, based on TechCrunch.

Although Lia uses biodegradeable material and eschews the plastic components typically utilized in these units, its test works in the same manner, based on the company’s website. The exam is made to identify high amounts of Human Chorionic Gonadotropin in urine, a hormone women produce whenever a fertilized egg attaches towards the uterus.

Chief executive officer Bethany Edwards cofounded the organization in 2015 with a few fellow classmates in the Integrated Product Design program in the College of Pennsylvania —Anna Couturier and Frances DiMare. Even though the biodegradeable nature from the test is really a plus for that atmosphere, the intention behind this method was to create a discreet test that may make sure the user’s privacy. Simplicity of use was another goal.

The diagnostics startup counts Ben Franklin Technology Partners and Dreamit Health as investors. It’s presently area of the Digital Health Accelerator in the College City Science Center in Philadelphia. Participants within the 12-month program receive $50,000 without getting to stop equity. Earlier this season it had been selected for any year-lengthy program with Springboard Health Innovation Hub for Existence Science companies.

Shannon Leaf, COO from the business, confirmed inside a direct message the diagnostics startup intends to sell the exam to consumers beginning in the center of 2018. Even though the biodegradeable pregnancy test is going to be on LIA’s website, it will likewise be offered on Amazon . com, based on the TechCrunch article.

The cost is consistent with rival test kits, Leaf stated. Customers may also create a donation to pay for the expense of tests for other women.

There’s been lots of curiosity about tests connected with pregnancy but frequently it’s been more associated with genetic screening to evaluate whether would-be parents have a very gene that will increase the chance of unintentionally passing along a harmful genetic condition, for example Natera, Counsyl, and others. But Lia Diagnostics founders contend there hasn’t been any significant innovation within the pregnancy testing space in excess of 3 decades.

MedCity ENGAGE, October 23-24 in North Park, concentrates on the most recent strategies and innovations to boost patient engagement, care delivery and company wellness. Use code MCNTAG in order to save $50.

Virtual Reality to deal with Post traumatic stress disorder: Interview with Todd Richmond, Director of USC’s Mixed Reality Lab

While Post traumatic stress disorder is really a major problem for a lot of of individuals serving within the military yet others who operate in traumatic situations, additionally, it affects huge figures of ordinary individuals who experience traumatic occasions for example assaults or disasters. Nearly 24 million Americans are afflicted by Post traumatic stress disorder at any time, and ladies are two times as likely as men to build up the problem. Post traumatic stress disorder can often be overlooked and it is apparently underdiagnosed, but panic disorders still cost society roughly $40 billion each year in treatment costs and lack of productivity.

A comparatively new choice for Post traumatic stress disorder therapy involves virtual reality, with the aim of creating multisensory, immersive environments and encounters to deal with the problem. The process could be controlled with a clinician to match a patient’s needs, and also the results to date are promising.

Medgadget had the chance to inquire about Todd Richmond, Director from the Mixed Reality Lab in the College of Southern California and IEEE Member, some questions regarding the idea of using VR for Post traumatic stress disorder and just how it’s labored to date.

Conn Hastings, Medgadget: Do you know us the way you grew to become interested and involved in this region?

Todd Richmond, College of Los Angeles: In early stages within my chemistry faculty career I started while using web along with other digital media within my teaching and research. That motivated me to resign my faculty position in 2000, where I dove mind on into emerging tech. That brought me to USC, where I’ve been since in a number of positions – I’m now in the Institute for Creative Technologies (ICT), where I mind the Mixed Reality Lab.  I additionally function as research faculty in the School for Motion picture Arts.

I’ve been employed in many forms of digital media — mostly as put on training and learning — in excess of two decades. The strength of these platforms has elevated considerably during the last decade approximately, and extensions into day-to-day existence across all sectors have evolved rapidly. Within the medical area, two colleagues of mine happen to be inspirational to utilize. First is Dr. Skip Rizzo, that has pioneered using VR for the treatment of Post traumatic stress disorder at ICT. He is experienced within the field, and has worked with VR in clinical settings for many years.

Second is Dr. Leslie Saxon, who’s a cardiologist with USC Keck Med school, and who heads the USC Body Computing Center, that is co-found at ICT. I’ve labored with Leslie for several years, and she or he is really a pressure of nature, working towards better health outcomes by using body sensors, big data, Virtual, Augmented and Mixed Reality (VAMR), along with other emerging technologies.

Medgadget: Beyond Post traumatic stress disorder, what kinds of conditions is virtual reality useful for?

Todd Richmond: An organization in the College of Washington has witnessed encouraging results using VR for the treatment of discomfort in burn patients (distraction therapy). VR supports the commitment of treating numerous mental issues for example acrophobia [anxiety about heights] (and actually many phobias), anxiety, and depression, in addition to Alzheimer’s and dementia.

Medgadget: Are you able to talk us with the technology as put on Post traumatic stress disorder? Will the patient put on a headset? Exactly what do they see and experience?

Todd Richmond: With Skip’s system, the Medical VR experience happens inside a clinical setting having a trained clinician (psychiatrist/counselor) present. The individual wears a VR headset, and also the clinician includes a computer interface where they are able to pick the patient’s location (typically Iraq or Afghanistan, given the newest conflicts), time, weather, and scenario. The clinician may then see exactly what the patient sees on the application.

Because the patient describes the traumatic event, the clinician can recreate the scenario for that patient to “relive” and sort out. The protocol follows established operate in exposure therapy, and, obviously, the clinician doesn’t just jump into an overpowering entertainment – rather, the individual works to the traumatic occasions with time, just like they’d with no VR. VR exposure therapy provides two major benefits – the very first is for that patient, as they possibly can become more immersed within their past occasions, which will help these to confront and sort out them.

The 2nd, and possibly more essential, is perfect for the clinician. Because the patient describes the problem and also the clinician visually/aurally recreates it, they may have a better knowledge of exactly what the patient experienced. As the saying goes, an image may be worth a 1000 words – as well as an immersive VR scenario may be worth much more words.

You should observe that Medical VR isn’t a “doc inside a box” fix. The machine is made for carefully controlled clinical settings having a mental doctor.

Medgadget: Just how can a clinician tailor the therapy for any specific patient?

Todd Richmond: The clinician includes a “clinician’s control center” of sorts, which enables these to “point-and-click” to produce a multitude of scenarios with various stimuli, situations, and much more.

Medgadget: How has got the system labored for Post traumatic stress disorder patients to date?

Todd Richmond: Studies have proven significant enhancements in nearly all patients. Although this is not really a “silver bullet,” as they say, VR exposure treatments are showing to become a effective tool that medical professionals may use aid healing individuals who are suffering from Post traumatic stress disorder.

Link: Mixed Reality Lab in the College of Southern California…

Health Wizz leverages blockchain technology to provide patients control of their data


Health Wizz is taking advantage of the growing blockchain trend.

The organization lately unveiled its platform, which enables customers to aggregate and share their personal health information.

The Falls Church, Virginia-based startup also took part in the Pitch Perfect contest at MedCity Participate in October.


Inside a recent interview, Chief executive officer Raj Sharma pointed to some couple of key explanations why Health Wizz made the decision to make use of blockchain technology to power the woking platform.

The first is the problem of security. “We as consumers have finished having faith in institutions with this data,” he stated. “For us, it had been really key that even if our consumers use our application, it normally won’t need to trust us. They need to trust blockchain.”

Furthermore, Sharma noted the startup wanted to produce a marketplace of health data where pharmaceutical companies, research organizations yet others can talk to consumers. Blockchain was a good way to create these connections happen and permit groups to liaise even if it normally won’t trust one another.

Health Wizz’s platform works as a result: Patients can observe and download their data from hospitals, their doctor yet others. Furthermore, specific organizations may use cryptocurrency to incentivize patients to lead their own health data for research. This currency comes by means of OmCoin, an electronic Ethereum token from Health Wizz. These tokens function as digital access keys, allowing users to switch information.

North Park-based MintHealth is yet another player on the market is leveraging blockchain similarly. Their lately revealed self-sovereign personal health record utilizes we’ve got the technology. Patients have access to MintHealth online or using a mobile application. Every individual includes a global identifier that enables these to access their information and oversee permissions into it. There’s also payer-funded digital incentive tokens known as vidamints, which patients receive once they take part in healthy behaviors. They may then make use of the tokens to assist purchase healthcare-related costs.

Sharma stated that although Health Wizz and MintHealth both use blockchain, the businesses will vary.

“We are utilizing an open Ethereum blockchain,” he stated. “We don’t really put data around the blockchain itself. We put keys around the blockchain. [The data] ranges from the participant towards the medical trial. It’s a really different approach meaning that … many others are speaking about putting data around the blockchain.”

Searching ahead, Sharma listed three key areas the startup intends to pay attention to.

First, Health Wizz really wants to make its tools simple to use and for that reason appealing to consumers. The 2nd step, which the organization has began, is normalizing the information so others have access to it. Finally, in regards to a year lower the street, the startup is fine with having 4 or 5 pharma or medical trial companies getting together with its consumers.

“If a couple of hundred finish users may take place in numerous studies, that might be really what we should would call success,” Sharma stated.

Photo: nonchai, Getty Images

Autorité générale pour le divertissement : le pianiste worldwide « Yanni » donne ses premiers concerts en Arabie saoudite

RIYAD, Royaume d’Arabie saoudite, December 3, 2017 /PRNewswire/ —

L’Autorité générale pour le divertissement (General Entertainment Authority – GEA) a annoncé que le compositeur et artiste multi-instrumentiste de renommée internationale, Yanni, se produira pour la première fois en Arabie saoudite.

     (Photo: )

     (Photo: )

Une série de six concerts aura lieu dans trois villes à travers le Royaume. Elle a démarré le jeudi 30 novembre et le vendredi 1er décembre dans la Ville économique du Return on investment Abdullah à Djeddah. Suivront l’ensemble des concerts plusieurs 3 et 4 décembre à l’université Princesse Nourah bint Abdulrahman de Riyad et, en raison en popularité du pianiste worldwide et en demande du public, deux concerts supplémentaires seront donnés au Center du Return on investment Abdulaziz pour la culture mondiale à Dhahran, le mercredi 6 et le jeudi 7 décembre.

La GEA a réagi à la forte demande du public saoudien, qui a fait preuve de boy grand intérêt, en augmentant la capacité du site pour accueillir le grand nombre de participants et en amplifiant le nombre de billets disponibles.

La GEA a souligné que Yanni, lauréat plusieurs Grammy Awards dans la catégorie « instrumentiste et interprète le plus remarqué et le plus talentueux », jouera ses morceaux l’ensemble des plus incontournables et populaires devant le public saoudien, pour la toute première fois en Arabie saoudite. 

En attirant ces spectacles de grand prestige, la GEA se fixe pour objectif d’offrir united nations programme diversifié d’actes de divertissement au public saoudien. Cet hiver, la GEA propose united nations calendrier de divertissement très spécial et précieux, intitulé #winter_roznamah.

La première visite de Yanni au Royaume d’Arabie saoudite fait partie de sa tournée mondiale 2017-2018 pendant laquelle il jouera tous l’ensemble des incontournables de sa carrière musicale qui a commencé en 1984. Ses concerts se caractérisent componen leurs effets audiovisuels, puisqu’il est célèbre pour boy émission de télévision « Live in the Acropolis ».

Yanni se produira pendant six spectacles de deux heures chacun, à Djeddah, Riyad et Dharan. Cette durée est en somme plus élevée que le temps moyen qu’il passe habituellement dans le cadre de toutes ses tournées musicales.

La GEA invite l’ensemble des citoyens et résidents d’Arabie saoudite à visiter boy site web roznamah de divertissement en cliquant sur http://world wide et à suivre boy compte officiel @Roznamah_sa sur toutes l’ensemble des plateformes de médias sociaux ou peut-rrtre un en téléchargeant boy application roznamah sur tous l’ensemble des smartphones à travers le lien, pour rester informés de toutes ses activités et évènements de divertissement hebdomadaires.

SOURCE The Overall Entertainment Authority