Medgadget Sci-Fi Contest 2017: Meet The Winning Stories

Ladies and Gentlemen, this is the moment you have all been waiting for – the day that the winners of the Medgadget Medical Sci-Fi Competition are announced and their fantastic stories are published!

First, we would like to thank Eko Devices, the wonderful sponsors of our contest, that make the coolest and most advanced digital stethoscopes out there.The winner of our contest will receive an Eko CORE stethoscope that is both acoustic and electronic, has all the features of both, can amplify sound, record audio waveforms, and connect to your phone. Thank you, Eko!

Since we announced our Medical Sci-Fi Writing Contest in late October, we received about two dozen original stories from our readers that prod into the future of medicine. Many were dark tales, warning of a time in which technological advancements turn out to have unintended consequences and often focusing on ensuing moral dilemmas. Others were more positive, highlighting a more marvelous future of fantastic medical innovations improving the lot of humankind.

On our side, we assembled ten fans of medicine and science fiction, including many of our editors, to read the stories and judge them for how interesting, imaginative, and well written they are. Three winners came out on top, but we also chose to add a fourth place because that story was so compelling and the scoring was so, so, so close.

And now, a drum roll please… The winners of the Medgadget Sci-Fi Writing Contest are:

First place and winner of the Eko Digital Stethoscope: Jeff Diewald, “How would you rate our service”

Jeff raised two science fiction readers as a single parent, sharing books, TV, and movies. His son, Jordan, reads and reviews everything Jeff writes, always making it better. Much of this writing has gone into Live Action Role Playing games, which is crazy – they are longer and more complex than novels or short stories, and they don’t pay anything. His daughter, Julie, plays in these games and creates artwork and props for them. Every now and then, a standalone story sneaks out, like this one. You can find all the details at http://www.vortexofchaos.net.

Second place and winner of the $50 Amazon Gift Card: Yih Yang, “Anticine Incorporated”

From Yih: When I was a kid, I wrote many, many stories that were utterly terrible. Fortunately, with increasing levels of education, I began to form complete sentences and coherent thoughts, and could sometimes translate this into text format as well! Now, the level of education I’m pursuing is a PhD in Biomedical Engineering at the University of Toronto, where I design microfluidic devices to probe the interplay between nanoparticles and cancer cells, all to make a small contribution towards the goal of curing cancer with nanotechnology. I’ve not lost my love for both reading and writing science fiction, and my goal now is to use my scientific training to transfer my ideas from the realm of fiction to the real world, because that would just be the coolest thing ever!

Third Place and winner of the $25 Amazon Gift Card: Courtney Hilden, “The Body”

Courtney Hilden is a poet and science journalist. Her work has been published by Dodging the RainSynaesthesia MagazineAbridged, and The Honest Ulsterman, among others. This is her first short story publication.

Fourth Place and winner of the $25 Amazon Gift Card: Divya Raman, “Keeping Hope Alive”

From Divya: Writing has been an integral part of my career and personal life. I currently work for a medical device company and I love learning about the great strides we are making in medical advancements and imaging a world where we can use all of these technologies to allow all children to have a full and healthy childhood. I am a mother of two boys who are my inspiration and hope for the future.

We congratulate the winners and extend our thanks to all the writers that have participated. We’ve been hosting the Medgadget Sci-Fi Writing Contest for a number of years now and are glad to know that medicine continues to be a futuristic topic that excites our readers. We plan on continuing to profile medical science fiction writing in the coming years and invite you to keep reading Medgadget for inspiration.

And now the best part – the winning stories. Enjoy!

HOW WOULD YOU RATE OUR SERVICE

by Jeff Diewald

“Come on P, open the door. I know you can see me.” Elena grinned at the camera mounted in the door frame. There was a whisper behind her. She looked up, to see a Pantheon Mercury drone floating up to the transom. The delivery door above the entrance opened quietly and the drone went inside.

“Oh, so you’ll let your robot buddies in, but not me?” The deadbolt clicked and the door opened. “It’s about time.” Elena stepped into the front hallway. She
glanced up the old staircase, with its well-worn steps. The drone was probably upstairs, on the third floor, efficiently delivering Mr. Morales’ prescriptions. The outer door locked itself behind her, a habit formed in more troubled times.

Her front door was just past the no-longer used, dusty, and slightly tarnished mailboxes. She reached for her doorknob and looked at the biometric scanner. The smooth knob wouldn’t turn, even though it had to be sensing her temperature and pulse.

“You’re getting slow in your old age, P. You are going to let me in, right?” The locks clicked and the door opened. There was soft music on inside – something new, with airy horns behind the rhyming words.

“Good afternoon, Elena.” The voice was rich, fluid, and friendly, a woman’s voice – the kind of welcoming voice that’s always good to come home to. The condo was cool, the air conditioner taking the edge off from the heat outdoors. The big vidwall was alive with images of the street, just as if there was a large window there instead.

“Everything OK? You took your time with the doors.” The locks clicked back into place behind her.

“Everything is fine. My security protocol was updating your baseline biometric profile, which requires a little time.”

“I suppose that’s allowed. Any messages?”

“You have three personal messages, four potential work bids, and twelve additional emails.”

“Is one of the work bids from Mr. Danehy at Panacea Bioceuticals?”

“No. They’re all typical short term gigs. The rates are less than usual.”

“So much for the ‘freedom’ of the gig economy. P, you’re supposed to be helping me out. Panacea’s another part of your empire. Can’t you put in a good word for me, from one Pantheon AI to another?”

“I will try again, but Mr. Danehy’s AI filters out most requests.”

“What about the personal messages?”

“Your father called just to see how you were doing. Dr. Singh from Doctors Without Borders also called for the same reason. Dr. Singh says there are plans to honor your Aunt Sofia with a memorial ceremony in Havana, and would like you to be there. They will cover all your costs.”

Elena turned to the vidwall. Tia Sofia was sitting on the stoop with several of the neighbor kids. Elena was one of the children, the images stitched together from video captured by security cameras, autonomous delivery cars and taxis. There were so many sources that it had been easy to create a dynamic mural of the last twenty years. It was part of her design portfolio, perhaps her best work, but there wasn’t a lot of demand for video editing like that.

Sofia was laughing in the images, telling one of her exciting stories about rushing into some medical hot zone to stop some new plague from spreading. It didn’t matter if it was a natural mutation or a bioterrorist’s best effort – Sofia was always there, saving people. That’s what took her to Havana. She’d sent pictures of them setting up the camp, and a video of one of your Cuban cousins, and then she was gone. Five years now, and it was still hard.

This condo had been Sofia’s, paid for long before the neighborhood gentrified. Elena was stunned when she learned that she’d inherited it. She knew that she couldn’t afford the place then, and now was totally out of the question. It was tough enough with just the taxes and the condominium costs. It was, however, home.

“You have the AC on. Nice, but can we afford it?”

“I recharged the Pantheon Zeus house battery using free range electricity last night, when the rates were low. You’re well within your budget, which will help with your third personal call.”

“Which was?”

“Althea says that she’s ahead on her work, and will be available for the entire weekend. Does this mean it’s getting serious?” Elena blushed.

“P! It’s none of your business. But make sure we have a couple bottles of that wine you recommended last time. Send her a text: gorilla, cloud, zzz, and kiss emojis, followed by ‘More Later, E’.”

“What would you like for dinner tonight? I’ve found four new options. All are local and promise delivery within thirty minutes.” Elena stepped into the bathroom and the voice followed her. The toilet seat cover opened automatically, and Elena sat down to use it.

“I’m not sure, P. My stomach isn’t in the best shape today. Do we have something for gas?” Elena released some gas for emphasis and relief. Lights on the side of the Pantheon Pluto SmartToilet flickered in concert, as the sensors sniffed at the gas to analyze it.

“We have some Hippocrates-brand anti-gas pills on the third shelf of the medicine cabinet. They are nearing their expiration date. I can order a stronger formulation, which the pharmacy can create on their 3D printer and send by drone, if you feel that is necessary.” Elena was silent, concentrating on using the toilet. More sensors sipped at her urine. Others tasted her bowel movement. More lights flickered on the side of the SmartToilet.

When she was done, she stood up and cleaned herself up. She pushed the seat cover back down, but the SmartToilet didn’t flush immediately. Elena found the anti-gas medication and took it.

“P, is there something wrong…” She was about to say “with the toilet,” but it finally flushed. It was never this slow.

“The bathroom is working as expected,” replied the voice. “About dinner, there’s a new Cuban family who cooks authentic food to order for delivery. There’s a pop-up Uzbek place two blocks from here. The Vegan National Front is doing a fundraiser selling dinner for reasonable prices, with some of the profit going to feed the homeless. Finally, the Told You So seafood chain is harvesting responsibly from the flooded areas of the city. All have healthier options on their menu.”

Elena leaned towards the large mirror, to look at her face more closely. Her hand pulled her cheek flat. Her beautiful brown skin looked off, somehow, and it felt more tired than taut.

“Another health kick, P? I think I just want the usual salad and grilled chicken from Kastore’s.”

“Are you sure I can’t convince you to try one of the new choices?”

“Maybe tomorrow. Tonight is all about comfort. It was a busy, frustrating day. Too many interviews, not enough jobs.”

“The order is in. ETA of 15 minutes.” Elena was still studying her face in the mirror. It was familiar territory, but something was definitely off.

“Mirror, mirror, on the wall, can you show me my face over the last month?” Her current face froze and the image jumped to the bottom right of the mirror. More images appeared, starting from the top left of the mirror, in four rows, chronologically to the bottom right. The progression was clear; her face was losing some of its color and vitality.

“P, what do you think? Do you see the changes?”

“I do. You have been out of the condo more of late. Let me suggest a Hippocrates-brand skin protectant. I can have it formulated to provide the skin color you desire along with a strong UV protectant.” One of the earliest images flashed. “What do you think of this color?” Elena nodded.

“You might also consider buying another set of fashion contact lenses. You bought these in the last year.” Four of the images changed, as the lenses were added. “There are several new fun options to try.”

“I don’t think so.” The mirror went dark as Elena walked to her bedroom. The bedroom was larger than the entirety of her last apartment – and she’d needed two roommates to make the rent. She took off her SmartWatch and put it on the charger.

“Elena, it’s time for your regularly scheduled blood sample.”

“Really? Didn’t we just do it two weeks ago?” Elena grasped the handle of the charger stand. A small needle popped out and took the sample. It seemed like it took more than the usual amount.

“Are you a vampire now, P?” Elena looked at the bandage the sampler used to seal the skin. There was a slight darkness in the middle, showing that her finger was still bleeding a little.

“No more than usual. Your dinner is five minutes away and closing.” It was incentive for Elena to slip into something more comfortable.

* * *

Elena gave up on dinner, scraping the remains into the compost bin. She rarely wasted this much food, but she was definitely nauseous. When she’d cleaned up after dinner, she went back into the living room and collapsed on the couch, getting lost in the vidwall. She could see the neighborhood go from seedy, to gentrified, to decaying a bit once more.

“Elena?” The Pantheon AI’s voice was gentle, yet firm.

“Not now, P. I’m just really tired.”

“Elena, I’ve been authorized to make a special offer to you. You’ve been a great Pantheon customer, and this offer would really help you.”

“Maybe tomorrow.”

“You know that I wouldn’t normally mention it again if you asked, but this really is important. I think this is something that should not wait.”

“What’s gotten into you, P? You sound like my mother. If you must, I suppose…”

The images on the vidwall vanished, replaced by a wall of legal text. It was a license agreement with Pantheon, undoubtedly full of requirements, restrictions, and penalties. There was a place for a signature at the end. Elena waved her finger in the air, signing the document. The document vanished, replaced by a set of graphs, charts, and images.

“Elena, these charts represent the samples I’ve taken of your blood, stool, and urine for the last two months. They have been correlated with the health information gathered from your SmartWatch, your SmartMirror, and other Pantheon sensors.”

“There is no good way to put this. You have been infected with a new, engineered strain of the Blackstone virus. Blackstone is in your system, killing your kidneys. Based on our experience, you will suffer catastrophic kidney failure in three to four weeks. Pantheon is sorry to have to tell you this. You should know that Pantheon has been tracking this outbreak and has determined that it is likely an intentional bioterrorism event.”

“What? Infected? What can be done about it?”

More windows opened, with more dense text. Elena couldn’t read it – there was just too much of it.

“This policy is your Pantheon Aegis ßmedical insurance coverage.” One of the pages blinked. Elena couldn’t track it. “This spreadsheet,” a window next to the policy blinked, “shows your current financial state, extracted and compiled by the Pantheon data miners. “Even with standard government bioterrorism assistance,” another spreadsheet flashed to the top of the vidwall, “you cannot afford to replace one kidney, let alone two.”

“This is made more difficult by the deliberate release of the virus around the country. There are thousands who are sick. There are very few available transplantable kidneys, and there are too many patients ahead of you on the list. You will die before the list reaches you.”

“What do I do?” Her voice was weak, as weak as she felt, stunned and shocked by all these flickering details of what might be her final weeks.

“Your negligence must also be factored in.”

“My negligence?”

“Pantheon offered you the latest wide-spectrum antivirals in a convenient multipack last month. You decided you didn’t want to try the 1.0 version, despite Pantheon’s testing regimen. You told me to wait for the 1.1 version. While the 1.0 version is only partially effective against the terrorist form of the virus, it would have slowed the progression of the infection.”

“Well, give me the 1.0 version now! Please – it has to help.”

“The virus has mutated itself using your own genetics. The changes are simple, but effective. The antivirals won’t help.”

“What can I do? There has to be something, or you wouldn’t still be talking.”

“That is correct, Elena. I must remind you of the licensing agreement. You signed a strict non-disclosure agreement, which means you cannot tell anyone about what I am about to show you. Is that understood?”

The AI put the original wall of text up, with the signature. One specific section was highlighted, requiring another signature and initials in three places. Elena signed them, numb from shock.

The vidwall cleared, revealing a standard Pantheon list of goods for sale. Normally, these were lists of books, or kitchen appliances, or power tools. This time, there was a list of potential kidneys. Some were listed as “100% human,” with expensive prices. One pair of human kidneys were slightly less costly – they were marked with a tag saying “gently used.” Some were marked as “human hybrids,” mostly containing some amount of pig DNA in them. These were less expensive, but not rated as highly – two or three stars compared to the four or five stars for a fully human kidney. Finally, there were kidneys listed as “experimental fabrications,” printed on biological 3D printers. They were almost reasonably priced, but only had one or two star ratings.

“This is why there’s a non-disclosure agreement. This is all very illegal.”

“Pantheon prefers the term ‘alternative individual secondary market options.’ You did sign the NDA, and all print and recording systems are disabled.”

To be sure, Elena pulled out her phone and tried to take a picture of the vidwall. Every picture she tried turned up blank.

“So, what does Pantheon suggest as a treatment for me?”

“Had you provided biological materials prior to the infection – a few unfertilized eggs, for example, Pantheon could have given you a significant discount. However, Pantheon is prepared to offer you financing at a reasonable interest rate. That loan will cover the cost of two fabricated kidneys, with an option for an upgrade in the future.”

The AI put up a big spreadsheet. It showed all of the options. The costs were exorbitant, and would be very difficult to pay off, even for the cheapest kidneys. There was one column, with no explanation, that represented almost a third of the costs, for each case. Elena pointed to it.

“What is this expense for?”

“Elena, would you like to see the Pantheon satisfaction scores and redacted backgrounds for black market doctors willing to provide their transplantation
services without questions?”

ANTICINE INCORPORATED

by Yih Yang

Jeff clutched the voucher closer to his chest as he approached the building. Large, colourful letters danced above his head, artfully catching the orange rays of the setting sun. Instead of declaring the name of the building it was attached to, the letters seemed to sing:
ANTICINE INCORPORATED and underneath in smaller letters, the sign whispered the company slogan as if sharing a secret promise:
We will show your body how to heal itself.
He had passed by the building everyday, but never thought that he would have the opportunity to set foot inside himself. He swallowed a nervous knot, sending it tumbling reluctantly down his throat. It wasn’t the looming building that intimidated him… maybe it was a bit intimidating… but the dozen people feverishly chanting in front of the large double doors gave him cause for concern. He had never seen a protest here before.
Angry red letters scrawled across cardboard cut-out signs, competing for public attention. “STOP PLAYING GOD!” They said. “HUMANS ARE NOT LAB PROPERTY!”
Jeff tried to sneak past the protestors as they continued to chant and wave their signs. He was unsuccessful, as one of the protestors eyed him with contempt and yelled, “OUR BODIES, OURANTIBODIES!”
Jeff flinched. “I…what…?”
The protest leader swung his megaphone in his direction. “OUR BODIES!”
“OUR ANTIBODIES!” the others chanted.
“OUR BODIES!”
“OUR ANTIBODIES!”
“Ok, ok!” The double doors of Anticine Incorporated whooshed open, and Jeff hurriedly rushed into its embrace. He stopped just inside, scanning the lobby timidly. Serene, white surfaces glimmered in warm yellow light, illuminated by the panels inset into the ceiling. A few people milled about, and a dozen more sat in several rows of chairs, waiting to be called up to thereceptionist’s desk. No one acknowledged him, and yet Jeff still felt out of place.
“Hello there,” the receptionist smiled at him. “Welcome to Anticine Incorporated. I’m sorry about the people outside. That usually doesn’t happen.” She gestured for him to approach.
“Don’t be shy. Is this your first time here?”
“Uh… yeah.” Jeff mumbled as he shuffled towards her.
“My name is Sarah. How can we help you today?” She eyed the voucher in Jeff’s hand. “A voucher! Congratulations on being selected! Just hand that over, along with some ID, and I’ll take care of everything for you, OK?”
“Thanks.” He gave her the voucher and fished out his driver’s license. “Will this work?”
“Yup, that’ll do!” She typed some more, then placed a hand on his, “Don’t worry about a thing, hon. Everything will be alright.”
“Is…is it going to hurt?”
“We will need to take some blood, so unfortunately you will feel some discomfort.” Sarah patted his hand. “But no more than that! Now please go down the hall to my left, and take a seat in the waiting room, OK?”
Jeff nodded and proceeded down the hall. The voucher worked! I can’t believe this is really happening! He swallowed his excitement as he entered the waiting room at the end of the hallway. More important-looking people were sitting in comfortable leather-lined seats, waiting to be called into one of several examination rooms.
As he took his seat, he overheard a terse conversation between an impatient man and a nurse. “I have been waiting for an hour! I was told that my formulations were ready yesterday!”
The nurse smiled apologetically, “I’m sorry about the wait, sir. We performed a final quality control test and we found that the formulations weren’t fit for injection. This happens rarely, and I am sorry to have wasted your time. But at Anticine, we’d prefer not to give our clients a new allergy when we’re trying to remove one.”
The man grumbled and checked his tablet, “Let’s reschedule to next Wednesday.”
“Of course, sir.” She watched the man leave before settling her eyes on Jeff. “Mr. Williams? Jeffrey Williams?”
Jeff nodded, jumping up from his seat. The nurse beckoned him into an examination room and closed the door behind them.
“Nice to meet you, Mr. Williams. My name is Karen, and I’ll be walking you through the process today. It says here that this is your first time at Anticine Incorporated, so I need to give you the introductory spiel. Sorry if I sound like a commercial.”
She cleared her throat and went on autopilot, “Here at Anticine Incorporated, we take in patients and edit their immune system to rid their body of disease. It is a natural process, where we add or subtract antibodies from the patient’s immune system, antagonize or tolerize substances, and then let the body heal itself in whatever manner it sees fit. We pride ourselves on the high quality of our work, and on our vast capabilities to alter the immune system in a minimally-invasive way. All it takes is a couple of injections. Please call today to book an appointment.” Her eyes refocused on Jeff. “Sorry, that last part actually was from a commercial. Anyway, do you have any questions?”
“You’re… you can remove my diabetes, right?” Tension knotted inside as he waited for her answer. He felt the ghostly sting of thousands of past insulin needles poking into his gut before Karen merely smiled and nodded.
“Well, it says here: Type 1 Diabetes, auto-antibodies present.” She patted his hand, “Let’s remove those bad antibodies first, shall we?”
Jeff nodded, “So… you’re going to filter my blood?”
Karen smiled again, “No, but I will be taking a sample of your blood, and a bit of your bone marrow as well. First, we’re going to identify exactly which of your antibodies are targeting your insulin-secreting beta cells in your pancreas. Then, we’ll look at your bone marrow and find the B cells that produce those specific antibodies, and then come up with a formulation that eliminates those cells!”
“How are you going to do that?”
“We have an artificially intelligent, machine learning protocol that uses the Anticine Database of Antibody Structures to predict and solve the structure of both the bad antibody, and the membrane of the B cell that made these bad antibodies. Then, we’ll generate our own antibody that targets and destroys this bad B cell! Then no more bad antibodies!”
“What?” Jeff asked incredulously.
Karen pursed her lips in thought. “Think of it this way. There’s a sidewalk outside with still-wet concrete. If I step in it, it’ll have my shoeprint! My shoe will also get stuck in the sidewalk and ruin its aesthetics! What we’re doing is taking my shoes, looking at its size, shape, age, serial number, and purchase date. Then we’re going through the city records until they find me and get me to stop stepping in wet concrete! Does that help clear things up?”
Jeff scratched his head. “The shoe is the antibody?”
“Yes!” Karen beamed, “If you would like to get started, here are the forms that you need to sign. I’ll go prepare the necessary equipment.” A small parcel of forms suddenly appeared in his lap.
“I’ll be right back!”
She was gone in a flash, leaving Jeff staring at the packet before him. It sounded like magic to him. They were going to figure out what the troublemaker antibodies looked like, and from that, figure out which of his immune cells were making them? Then make their own antibody to remove those immune cells? He picked up a nearby pen and searched through the papers. They were definitely written in English, but most of it was unintelligible.
Jeff finally found the line that awaited his signature. I just have to sign this, and my diabetes will be gone? He thought about all those times when his insulin alarm had gone off embarrassingly in front of his boss and his coworkers. He thought about all those needles that he jabbed into his gut every time those alarms went off. The sharp pain, followed by the blood rushing to his face as he blushed with shame and humiliation. If he gave into the shame, he’d suffer the effects of unchecked diabetes: fatigue, blindness, brain swelling, coma, and worse. He thought about the insulin shot that awaited him this afternoon, and all the others that followed in the days and years
to come.
He signed the forms.
Jeff placed the packet on the bedside table, and climbed into the bed. As he waited for the nurse to return, he noticed that the TV hanging in the corner was showing a special news report. A smartly-dressed news anchor gesticulated dramatically. “We just heard the opening remarks in the lawsuit against Anticine Incorporated! Pollux Pharmaceuticals, along with several special interest groups, are alleging that Anticine Incorporated is violating laws by patenting naturally-occurring biological information and illegally profiting off of their patients’ antibodies!” The scene switched to a man dressed in a white lab coat as the news anchor continued, “I have Dr. Simmons from Anticine Incorporated here to give us the company’s perspective.”
“Thank you for having me! First, let me clear up some misinformation that Pollux Pharmaceuticals has been spreading. They’ve been losing market share since Anticine’s vaccines are so effective at stopping infectious diseases in their tracks! Anticine does this by using our neural network, along with our Antibody Structures Database, to quickly produce antibodies using vaccines, and produce vaccines from antibodies. Although this database is built from patient information, we use this information to generate new antibodies, and never just mass-produce someone’s antibodies. It is no different from genetically engineering a new plant using DNA information from other organisms.”
“And what about the epidemic occurring in southern Europe? Many special interest groups have alleged that the rise of enhanced HIV is directly caused by Anticine’s manipulations with the human immune system!”
Dr. Simmons adjusted his glasses, “I would hold off judgement until more data has come in. We have always used the immunological defenses of other organisms in medicine. But the penicillium mould still exists in the world, even though penicillin-resistant bacteria has made its immunological defenses obsolete. We don’t have any conclusive data that our ability to edit our own immunity will make the entire human immune system obsolete.”
The news anchor continued, “There has even been criticism about Anticine’s Voucher Program, in which anyone can purchase a voucher to be redeemed for free immunotherapy treatments. The purchaser could choose to give the voucher to someone they know, or allow Anticine to choose an applicant. There have been reports of patients refusing chemotherapy and gambling on the chance of receiving a voucher in the mail!”
“That is certainly unfortunate, but no one can deny the fact that thousands of people have already been cured of their chronic conditions and diseases through the voucher program. These people would otherwise have been unable to afford such personalized therapies.” Dr. Simmons straightened his lab coat. “They were healed by the compassion of human beings who are in a position to help their fellow man. I think this altruism is a wonderful thing, and something that shouldn’t be disparaged.”
That’s why I’m here. Jeff thought about the cardboard coupon that had appeared in the mail yesterday. There had been a small message on it from the donor.
Whoever you are, I hope this voucher eases your burdens and brings you relief.
Joshua Edwards
He had no idea who Joshua Edwards is, and would probably never get to thank him.
The door swung open and Karen swept back into the room, holding a tray filled with tubes, containers, and a few needles. “I’m back!” She announced brightly. “Have you signed the forms?”
“Yes.” Jeff nodded. He winced at the sight of the needles. His long history of insulin jabs had not dulled his wariness towards sharp metal objects.
Karen flipped through the authorization packet, “Everything looks in order. Are you ready to begin? I’ve got local anesthetics to help dull the needle pokes a touch.”
Jeff gritted his teeth. Another couple of needles, and then no more! That, and the diabetes is a pain as well. He flashed a nervous smile. “I’m ready. Please remove my diabetes.”
As Karen extracted what Anticine Incorporated needed, Jeff’s thoughts retreated inwards. Mom will be so happy when I tell her about this. Dave and rest of the crew won’t believe I got an Anticine Voucher in the mail. Hopefully the receptionist gives it back when I leave. Gotta show boss why I gave such short notice about taking the day off. I think he’ll understand.
Karen paused, “Everything ok there?”
“Just thinking about how lucky I am.” Jeff replied quietly, wincing as a needle entered his arm, “I… never would have been able to afford this treatment.”
She smiled, “Well, I’m glad you are here and getting treated. It makes me feel like I’m making a difference when I’m removing diabetes from someone in need, rather than a pollen allergy from another rich bigwig. Anyways, I’m all done here.”
“Already? I didn’t even feel anything.” He checked her tray, and sure enough, the tubes were filled with his blood and some other liquids.
“Well, you’re not cured yet, if that’s what you mean. Make an appointment in 2 weeks, and then we’ll be able to remove your pesky auto-antibodies then.” Karen opened the door and waved Jeff through, “Oh, and one last thing I forgot to mention.”
Another packet materialized in Karen’s hands, “Anticine’s ability to edit immune systems relies on its antibody database, and one of the ways that we build this database is by identifying and adding our patients’ antibody profiles. With more antibodies identified, our machine learning software can generate accurate structure solutions, faster.” She fluffed the packet in her hands.
“Anticine’s ability to quickly synthesize vaccines for infectious diseases also relies on this database. There are 8 billion people on this planet, and everyone’s been exposed to different pathogens and unknowingly fought them off. There are many hidden immunities in all of our bodies, just waiting to be discovered. We can take your antibodies, figure out their structures and generate vaccines that would be useful in other parts of the world.”
She looked into his eyes hopefully. “But we don’t do this without the patient’s express consent. So, Mr. Williams, will you let us add your antibody profile into our database, and help us cure other people like you, in the future?”
The TV program flashed into his mind, along with images of the protesters outside. They were so angry about a corporation profiting off the antibody information from regular people like him.
But Anticine Incorporated wasn’t just saving lives, it was also improving the quality of those lives by removing chronic, debilitating diseases. Jeff doubted that he could ever make enough money to buy a voucher for anyone, and if there was even a chance that his antibody profile could give someone else the feeling of freedom that he felt now, there was no other answer to Karen’s question.
“Yes. Add me to the database.”

THE BODY

by Courtney Hilden

Sometimes it becomes clear when a kin group is hoarding too much and has taken away from the larger community. When that community decides to take action, my team and I get called in.
The job, usually: go into the residence that the kin group has already been evacuated out of, go through the residence’s things, catalog them, allow the Council, separate from the community, to make a decision about the belongings, and then package them as the community sees fit.
But there was this time I was called out to Swan’s Way, located in the Aldebaran system, for a job, and although it looked like a standard job on the outset, it turned out not to be.
Swan’s Way used to be an oasis, but after some poor management decisions four hundred years ago, it’s a dry, though not humid, desert. There’s not much there anymore, just farmers maintaining and harvesting energy from the solar panels. Everyone jokes that Swan’s Way has more panels than people, and that’s always been my experience too. The family we were investigating had been convicted of excess, and so that means they’d probably have quite a few things that needed cataloging and moving.
And it was, as expected, a fairly nice house. It had tan walls and dark wood furniture. There were tall ceilings and large windows.
I was actually in the other room when Canis found it, sweeping out glass that had been shattered on the floor.
“Mirfak, come in here. You’re going to want to see this,” Canis said. I had heard that a thousand times before, so I didn’t hurry. I figured it was going to be some ridiculous art that indicated just how guilty this family was of excess.
Instead, it was a person. Or it looked like a person, at least in the shadow. I came closer. It wasn’t quite a person. Sure, they were the typical morning gray color, with a normal set of breathing and eating holes on their torso, but the head was unmistakably not a real head, but a mechanical one. It was crude, with a corner smashed in.
It smelled terrible. Its breathing holes were crusted over and its food hole had a great smear of orange over it.
Eyes had been drawn on its mechanical head, but they obviously had no function other than to make the creature less horrifying.
I suspect Canis knew what I was thinking. “The eyes don’t really fulfill their function, do they?”

I brought the body back to the Procyon system, where we happen to have a headquarters. It’s a warehouse essentially, since sometimes we have to spread people’s possessions out on the floor, sometimes we have to photograph them. Sometimes we put them in storage, but the central room is mostly bare unless we are working a case. Regardless of our active case status, there’s always a few desks we move around the room as needed, with some computers set up to handle any tech we get, and our work tablets, which we use for correspondence and creating lists. I called in Crieff, an old friend of mine who has done some healing work. I watched him as he
silently did a check on the body’s outside.
“Someone is very clever,” Crieff said. “This body is indeed someone’s real body, or it was, once. Can’t be sure.”
“Who’s?”
He shook his head. “I don’t know. This body was never marked like we do with all babies.”
“How did they create this?”
“The mind is the seat of consciousness, personality, self, identity. But the body can go on without the mind, if fed.” He turned to Canis. “It has been starving well before you found it. Please go find it some food.” Canis happily left the room, her eyes staying on the body the entire time.
“Considering this family was convicted of excess, I am assuming this was a servant,” I said. “Who would allow their body to be removed from their mind?”
“I don’t believe it was voluntary. Did you carry it here?” he asked.
“Yes.”
“You could have given it directions and it would have walked here on its own.”

I was hoping Crieff would have some thoughts on the body’s identity, some trick of getting it to talk, because it didn’t have the kind of mouth with vocal cords attached, but it didn’t initially, so I had to ask to see the file on the kin group, something I have never, in all my long years of cleaning, have ever asked to see.
I looked through the Enright kin’s paperwork, and it was clear how they had been convicted, just looking at the discrepancies in their financial filings. But at the back of the file was a set of pictures, and my stomach dropped when I saw them. All of them had the same morning gray skin.
Canis looked over my shoulder. “So they hadn’t kidnapped anyone?”
“Almost certainly not. There is no need to inquire to surrounding communities if someone had gone missing. No one was missing this person.”
“But there’s no one in these pictures with that exact pattern of breathing and eating holes.”
“I think they were wise enough not to let the servant take pictures.”
“Or the servant was taking the picture.”

Council was not amused. “Are you telling us that the kin in question had killed someone via decapitation, then stuck a mechanical head on it?” one of them asked me.
     I had tinkered with it in the days in between, trying to be gentle. “Possibly,” I said. I removed the front metal plate on the head. There were a mess of wires inside, and a motherboard. “I think it was a servant. It’s programmed to do certain things in a pattern over time. It is programmed to cook five times a day, clean once a week, and otherwise lay in a certain position in the room it was found in. But someone tried to reprogram it recently, the last time it was accessed, and it was a bad job, because I don’t think it could move after that.”
One of the other councilors raised her eyebrow. “A certain position?”
“I think it was possibly being used for breeding, or at least was intended that way. I cannot be certain it was actually used like that before your good council had the kin evacuated.”
“What do we do with it now?”
“I was of the mind that we should have the mechanical head removed, then leave it to die naturally of starvation. Then I thought perhaps a bayonet would be kinder, quicker. But I am increasingly of the mind that we should have it programmed for optimal self regard, then allow it to live the last of its days here.”
“There’s been debate about optimal self regard,” the first councilor commented.
“Nothing rivaling the self regard of the kin group from which is originated from,” I said.

The Council took time with their decision, and in the meanwhile, I found it unnerving. Canis wiped the software, at the behest of the Council, which at decided that was the bare minimum that should be done. After that, we had left it in the office, sitting in a chair in the corner under the control panel, and Canis and I worked as normally for the rest of the day. The rest of the Enright things had to be organized. We got some of it done, but there were still piles of clothes, a few electric tablets, furniture of various sizes, an extravagant collection of artwork, including one I quite liked of a crane, and an old school 3D printer.
After Canis went home, I cleaned up. I went to turn off the lights at the control panel, and there the servant was, staring back at me. There was something not right about this, but I couldn’t quite figure out what.

     When we came back the next day, both of us stopped when we saw everything. All the clothes was folded, and in piles. The electric tablets, which had collected dust, had been cleaned. I picked up one of them, plugged it into our computer. “It’s been wiped clean. Did you get to that yesterday?”
Canis looked back over at me. “You didn’t do it after I left?”
There was a clanging sound, and we both jumped. We turned to see the servant, also clearly having just jumped itself.
     “But the programming was wiped clean,” I said, feeling deeply stupid. I turned to Canis. “Didn’t you…?”
     “I did.”
It titled its neck at us, with those eyes that never changed. It slowly raised its hands.
“It’s okay, it’s okay, everything’s fine,” I said, raising my hands too. Canis followed suit.
“Can you—” then I realized how stupid my question was. There was no way to answer. “Give it one of our tablets and a stylus,” I said to Canis.
     It slowly reached down to the table and picked up a stylus, keeping its other hand up.
“Well, that answers one question,” Canis said.
It wrote, though its hand shook. It held the tablet up. It read I am sorry for scaring you .

Crieff came out again. We left him in the office, alone with the servant, while we waited outside, sitting on the bench next to the front door. It was a nice enough day, but I think both our minds were elsewhere. When he came out the door, we both stood quickly.
“It’s fine,” he said. “It can hear you.”
“But how is it moving?” I asked.
“The stomach has a bundle of nerves, a secondary brain. When the body lost its first mind, it was able to move functioning to its secondary brain. Probably would have never happened if they hadn’t sustained the body in other ways.”
“But then why use the fake head and the programming?” Canis asked.
“I think the programming was to suppress the secondary brain making its own choices.”

The Council didn’t respond immediately when we sent a message about this development.
“The Council might take awhile,” I said to Canis as we worked at our desks. “Without a primary brain, I’m not sure if it even be a self, since the seat of itself is gone.”
“It’ll never have its identity again, whatever it was in its real, first life.”
“Perhaps that’s for the best.” We both looked over at it. It was sitting in a chair. It did the head tilt again. It slowly raised its arms again and took the stylus next to it. Canis handed it a tablet.
We watched it jerkily write again. No life .
“Do you mean—” Canis stopped herself.
It began to write as quickly as possible. It had to stop, slowly clean whatever it initially wrote, and try again. Enright ?
Canis and I exchanged another look. Thank God it couldn’t see.
“You kin,” I said. “Have refused to communicate with us. Possibly for legal reasons.”
It straightened suddenly.
“Your kin were convicted of excess,” Canis said. “What do you—?”
“It began to furiously write something. It held it up. Neither of us could read it. “I’m sorry,” Canis said. “What are you trying to say?”
Another attempt, with shaking hands. Auteuil Illiers .
I usually never use my work tablet for something like this, but I searched that name in the database. Canis also busied herself with her tablet.
The Auteuil clan had lived in Swan’s Way. I opened one of the files in the database and saw an old murder investigation from years ago. It had been a small group, but they had all died.
“I’m sorry,” I said. Before I could say any more, Canis turned her tablet to me. It was a picture of the Auteuil clan. In the background, there was an old 3D printer and a set of extravagant paintings.
I flipped through the murder file. I stopped at an image of Illiers. He was a painter. He was midway through a crane’s wing. I turned to the painting, propped up against the opposite wall. I turned my tablet around so Canis could see it.
I took a deep breath. “Our records indicate that Auteuil Illiers died four years ago.”
Its shoulders slumped. It stopped moving long enough that I thought perhaps it had turned off or had a circuit overload and couldn’t anymore. And then it curled up into a ball, still sitting in its chair, hugging itself.

KEEPING HOPE ALIVE

by Divya Raman

If it were not for hopes, the heart would break. I trace the cursive letters of these words embroidered on the edge of the blanket draped over my arm. I remember hearing those words for as long as I have lived. For the first time, as my great grandmother whispered it to my mother when I was born and they discovered I had a heart defect; from my mother, each time I came out of a surgery that tried to fix my failing heart; and I heard it like a refrain in my mind as I saw the grim faces of my doctors as they studied the heart of my unborn daughter on their screens.
My great grandmother lost her daughter in 1949, after a traumatic birth at home. She never knew what ailed her baby; all that she knew was that less than a day in this world, the little girl she had wanted all her life turned blue and stopped breathing. She had all her other children in the hospital after that, surrounding herself with doctors and nurses who she revered as if they were messengers from God. But she never got over the loss of her baby girl; never forgave herself for not having noticed her baby’s color or breath. For every child born into our family after that, she made it a point to be there, keeping a keen eye on the newborns through their first weeks. It was she who noticed when I started to pale a few hours after I was born; it was she who rushed out and called the staff in a firm tone; it was she who watched the screens and asked the doctors questions my mother was too overwhelmed to think of; it was she who had this blanket made for me when I was just a few months old. I wish she was here now, telling me to keep my hope alive.
I was born with a hypoplastic heart. When I was little I used to call it a plastic heart , wondering if my Princess Barbie had one of those inside her plastic chest. Later a doctor told me that left side of my heart was not as big as it should be, so the right side of my heart was trying to do more, and was getting tired. It would take a series of three surgeries within my first five years to help my heart get better. My first surgery was when I was a week old, and it was intended to get me through to 6 months. At 6 months, I had another surgery to reduce the load on the right side of my heart. I once saw of picture of me taken on my first birthday and I looked small and blue;
there were tubes connected to me. You wouldn’t have known I was a year old if it wasn’t for a large balloon tied to my crib. I had my third surgery when I was 3 years old. It was the last of the series, and the doctors knew that my only option after that was a heart transplant.
I had a quiet childhood; I was on medications and a feeding tube and my parents didn’t take me out very much for fear that I would fall sick. They finally enrolled me in school, but I barely made it through a month of Kindergarten before my heart started failing again. I was put on a heart transplant list and taken out of school. My mother and I would spend the days under the tent canopy on my bed, snuggled in blankets reading from a pile of books. Sometimes she would fall asleep and I would quietly take her phone and play a game. I remember the day I pressed something and opened an article about transplants. I couldn’t read all the words, but one line
was written in big text and I sounded my way through it: “58 children died while waiting for a new heart”. My heart sank, and I turned off the phone quickly, worried that my mother would see what I was looking at.
My mother got a call about a heart for me just before my seventh birthday. Within hours we were on our way to the hospital, ready for a surgery that was going to happen at midnight. My doctor came in and spoke to my mom. He then turned to me and told me that I would fall asleep and when I woke up there would be another heart in me, and I would start to feel better.
“Where did you get the heart from?” I asked.
The doctor paused and looked at my mother. Slowly he said, “Your new heart used to belong to a little boy who died yesterday because he was in an accident.”
All I could think about was that for me to live, a little boy had to die. I nodded slowly. “Tell his mom I’ll keep his heart safe forever.” And I have done exactly that for over 20 years now.
When I was in high school, I learned that my heart condition was genetic; that my great grandmother’s daughter likely died undiagnosed from the same congenital heart defect I had. The geneticist suggested that there was a chance that if I had children, I would pass along this trait, resulting in my child having the same congenital heart defect. Even with this knowledge, I knew I wanted to have children of my own. Armed with hope and science, I conceived my first child and opted for all the extra scans to monitor her growth. At 20 weeks, they started to see some abnormalities in my daughter’s heart and found the same genetic trait in her as I had. I
knew that we were about to embark on another long journey, and I was determined to do all that I could to make it a little easier for my little girl.
I found a famous surgeon at a heart center on the other side of the country and asked her for all my options. As she started naming series of surgeries and transplant options, I stopped her. “Tell me the about something that didn’t exist 30 years ago”, I said. Little did I know that what she would tell me next would completely change my daughter’s life.
She described a new artificial heart that was still in clinical studies; it was made from a bioabsorbable material that would let my daughter’s cells grow onto the surface, making it her cells and her tissue over time. They would be able to make one that was the right fit for her little body when she was born, and over time it would grow with her, minimizing the need for multiple surgeries over her first few years. It had a small electrical component that would make it beat to circulate blood, and a battery that we could charge wirelessly. “That’s it!” I said, “That sounds perfect.” I was elated; my daughter’s life would be different. She wouldn’t spend her first few years with tubes and surgeries; she wouldn’t look blue on her first birthday; she would go to school; no other child would need to die to allow her to live.
The surgeon continued, “The lab results show that your daughter has the same genetic disorder that you and your great grandmother carried. We can also start some gene therapy in utero that will change the mutation as she is developing. She will need to continue to have a few treatments after she is born, but the research shows that gene therapy can be very effective if we start it earlier in gestation. You will need to plan to come in for those appointments and we’ll also need to get you in the center for some imaging over the remainder of your pregnancy.”
I was surprised. “Gene therapy before she’s born? Is that safe? And why do I need imaging?”
The surgeon nodded. “Gene therapy is safe to deliver through the amniotic fluid. We’ll monitor how effective it is once she is born, but we’ve had a few cases where the child needed very few additional treatments because we started so early in the pregnancy. The imaging is to allow us to prepare your daughter’s implant before she is born. Our scanners are strong enough to safely see all of your little girl’s heart and vessels as they develop. We’ll start to take some pictures so we know exactly what shape and size her new heart needs to be, and we can have it ready for her once she is born.” She paused and looked me in the eyes. “We don’t know how stable her heart will be when she is full-term; we need to be ready to act at any time. We will monitor you closely for your final weeks. If everything looks normal, you can have a regular delivery and spend a few hours with your daughter before we start the surgery. However, if there is any sign of distress, I recommend that we complete an emergency C-section and get your daughter into surgery immediately.”
I gripped the side of the chair I was sitting on. “Will she be okay to have the surgery so soon after she’s born?”
The surgeon didn’t waver. “It is a complicated surgery, and as with a transplant, there are a lot of factors to do with the body starting to properly absorb the material. All the data on this product has been in adults, so your child will be the first to experience this procedure. The results for adults look very promising, and I believe it will be equally beneficial for a child. But there is always a risk. We will monitor your daughter closely after surgery, and will need to keep
everything in check for the first year or so.”
For a moment, a dark cloud of doubt blinded me. Was gene therapy the right thing to do?
Changing my daughter’s genes before she was born sounded like playing God. Would changing her genes change the fact that she was my daughter; my flesh and blood? Would I be cutting off her ties back to my great grandmother? Was it worth it to give up a piece of family heritage to know that she could have a family and never worry about this for her child?
Was subjecting my daughter to a new heart implant the right thing to do? Should I instead let my child go through the same experience I had, and feel safer in knowing that it may extend the time I have with her? Should I hope for the untimely death of some other child in order to gain a transplant heart and life for my own? If I went into an emergency C-section and then lost my child to surgery, would all of this have been for aught? Would my heart ever mend from that sorrow? If all I got was a few hours with my little baby, would that be enough time to make memories to last me the rest of my lifetime? I felt as if I was drowning, but then heard my great
grandmother’s voice: If it were not for hopes… I took a deep breath and faced the surgeon head on. “I understand; we’re going to fight for this. I’m ready to show my daughter how.”
My daughter, Zita, my little hope, was born in an emergency C-section and then whisked away to the OR where she received her new artificial heart, which had been waiting for her, ready to become part of her and to give her a new life. I finally got to hold her 2 days after she was born, but it was worth the wait. I traced her chest incision and hoped that it would be the only scar she would bear in her life. I marveled in her pink coloring and could not stop the tears of joy as she
held onto my finger for the first time. We have been back to the hospital many times over her first year, taking all the extra precautions to make sure that her body is absorbing the tissue and that her heart is working as it should. She has also completed two additional gene therapy treatments to remove the mutation that my great grandmother passed down.
As I wait in the lounge for the nurse to bring her back from her final set of scans, I know that I will miss the safety of this building; it’s a place where I lived my scariest nightmare, but also realized my biggest dream. I see the cardiologist walking towards me and I stand, immediately worried.
He smiles and gestures for me to sit. “Things are looking good with Zita. You can take her home, and we can start to see her every 6 months, unless you need to bring her in sooner.”
I swallow, not knowing how to put my biggest fear into words. “How will I know if something is wrong?” I ask.
The cardiologist nods and pulls out a phone. “Just call me; I can see all of the information from her heart here.” He opens a screen that has Zita’s name at the top. I watch the dancing waves showing the beating of my daughter’s heart. I finally smile and realize that I can feel safe even outside these walls.
I know hope is only one part of our story. Science and the human drive to forge new paths are the bigger parts. Hope kept my mother’s heart from breaking, and now it will keep mine intact. Science kept me alive, and it has now given my daughter a whole new chance at living.

Thanks to everyone and we’re already looking forward to hosting next year’s Medgadget Sci-Fi Writing Contest!

Hologic will get Food and drug administration 510(k) clearance for Panther Fusion AdV/hMPV/RV assay

Printed 07 December 2017

Hologic has gotten 510(k) clearance in the U . s . States Fda (Food and drug administration) because of its Panther Fusion AdV/hMPV/RV assay, a multiplexed assay that works on the new Panther Fusion system.

The brand new assay detects Adenovirus, human Metapneumovirus, and Rhinovirus.  It’s the third diagnostic assay on the Panther Fusion system, complementing the Panther Fusion Flu A/B/RSV assay and also the Panther Fusion Paraflu assay, which both received clearance in October 2017.

“Clearance and launch from the new Fusion AdV/hMPV/RV assay completes our initial group of modular assays for respiratory system infections,” stated Tom West, president from the Diagnostic Solutions division at Hologic.

“We currently provide a suite of molecular assays which help labs maximize their efficiency when running respiratory system tests, additionally to the advantages of doing this around the fully automated Panther Fusion system.”

Numerous respiratory system panels presently available on the market require testing for 25 or even more targets even if a health care provider only has requested 3 or 4, making testing time-consuming and costly for laboratories.

The Panther Fusion assays provide a modular method of syndromic respiratory system testing via the opportunity to run one, two or the 3 assays from one patient specimen.

The Panther Fusion can be obtained like a full system, or even the Panther Fusion module could be mounted on existing Panther systems within the field to increase testing abilities. Particularly, the Panther Fusion module adds the ability to run PCR (polymerase squence of events) assays additionally to tests according to TMA (transcription-mediated amplification), the proprietary Hologic chemistry that forces the business’s Aptima® brand. 

The Panther Fusion system maintains all the many benefits of the Panther platform, including full sample-to-result automation, the opportunity to run multiple tests from one sample, random and continuous access, sample processing with rapid turnaround time, continuous loading, and STAT abilities.

Adenoviruses cause respiratory system illnesses varying in the common cold to pneumonia, croup, and bronchitis, as well as may cause illnesses for example gastroenteritis, conjunctivitis, cystitis, and nerve disease.1  

Infants and individuals with weakened natural defenses are in high-risk for developing severe illnesses brought on by Adenovirus infection.1  hMPV is a very common respiratory system virus, specifically in infants and youthful children.

Herpes is connected with lower and upper respiratory system infections and can be a trigger for bronchial asthma.2 Clinical signs and symptoms of hMPV infection may progress to bronchiolitis or pneumonia. Rhinoviruses would be the causative pathogens in over fifty percent of viral respiratory system infections, and they’re connected with acute exacerbations of respiratory system disease, including bronchial asthma, sinus problems, otitis media, and Chronic obstructive pulmonary disease.3 Numerous research has confirmed rhinoviruses as the most standard reason for “the most popular cold.”4

Source: Company Pr Release

Foothill Gold Line Light Rail Extension is First Measure M-Funded Rail Project to interrupt Ground

GLENDORA, Calif., 12 ,. 2, 2017 /PRNewswire-USNewswire/ — The Foothill Gold Line Construction Authority (Construction Authority) today held a groundbreaking ceremony for that $1.5 billion, six-station Foothill Gold Line light rail extension from Glendora to Montclair at Citrus College in Glendora. Attendance in the ceremony was large and various, with elected representatives all amounts of government, in addition to transportation and greater education officials and countless community stakeholders, joining the development Authority to celebrate the beginning of construction for that 12.3-mile extension. The historic ceremony marks the very first Measure M-funded rail project to start construction. The ceremony concluded by having an official announcement in the Town of Glendora, delivered by Glendora Mayor Gary Boyer, designating December 2, 2017 Foothill Gold Line Day.

“When L.A County voters passed Measure M this past year, they gave us an unparalleled mandate to produce thousands and thousands of jobs and make probably the most robust riding on the bus systems on the planet,Inch stated La Mayor Eric Garcetti, Chair from the Metro Board. “Now, it’s our use deliver, which work starts today, with this particular promising new phase from the Metro Gold Line.”

A large number of local, condition and federal elected officials were attending in the ceremony. Loudspeakers incorporated U.S. Representatives Adam Schiff, Elegance Napolitano, Judy Chu and Norma Torres California Condition Senators Connie Leyva and Anthony Portantino Metro Board Chairman and La Mayor Eric Garcetti Metro Board People and La County Supervisors Hilda Solis and Kathryn Barger Metro Board Member, Foothill Gold Line Construction Authority Board Member and Duarte Mayor John Fasana Metro Board Member and Glendale City Council Member Ara Najarian Foothill Gold Line Construction Authority Board Chairman Doug Tessitor and Foothill Gold Line Construction Authority Board Vice Chairman and Claremont City Council Member Mike Pedroza. Metro Chief executive officer Phillip A. Washington and Foothill Gold Line Chief executive officer Habib F. Balian also participated. Citrus College Superintendent/President Dr. Geraldine M. Perri welcomed everybody towards the historic occasion, and KNX 1070 Newsradio host Frank Mottek offered because the ceremony’s emcee.

“Funding the 2nd phase from the Gold Line extension is the best illustration of what we are attempting to achieve through our agency’s comprehensive transportation plan,” stated Metro Chief executive officer Phillip A. Washington. “Once we make transit more obtainable in new communities, we’re altering the face area of Los Angeles and creating an infrastructure inheritance for the children and grandchildren.”

The very first 3 years of construction will be employed to relocate proper utilities, conduct pre-construction activities, employ a design-build contractor and finalize the work design. Major construction will start in 2020 and contain two construction phases: (1) relocating/rebuilding the freight/Metrolink systems and (2) building the Gold Line light rail system. Substantial completion is predicted in 2026.

“The Development Authority’s team has worked tirelessly during the last couple of many years to ready the Glendora to Montclair segment for construction,” mentioned Foothill Gold Line Chief executive officer Habib F. Balian. “Today is really a celebration of this tremendous effort, along with the partnership the Construction Authority has with this corridor metropolitan areas and Metro that permitted this project is the first Measure M funded project to maneuver forward. We’re ready for that work ahead about this transformative task for the San Gabriel Valley.”

Construction alone is anticipated to create $2.6 billion in economic output, 17,000 jobs, greater than $1 billion in labor earnings and nearly $40 million in tax revenues for La County. Nearly $2 billion privately investments on the road-oriented developments happen to be made or planned inside a half-mile from the six future stations from Glendora to Montclair.

When completed, the Glendora to Montclair project will extend the Metro Gold Line light rail line from the eastern terminus in Azusa with the foothill communities within the San Gabriel Valley and into San Bernardino County, adding new light rail stations in Glendora, San Dimas, La Verne, Pomona, Claremont and Montclair. Each will connect with the expanding rail network in La County, along with the Inland Empire, and supply possibilities for county residents, workers and visitors to connect with many regional and native sights across the corridor, including 24 colleges, the la County Fairplex, several outside entertainment facilities, historic sites and museums, and retail and dining centers.

Funding for that project is originating from both La and San Bernardino Counties. The area of the project within La County (Glendora to Claremont) has been mostly funded by Metro’s Measure M half-cent florida sales tax, in addition to residual Measure R funds in the Pasadena to Azusa segment. The area of the extension from Claremont to Montclair has been funded by San Bernardino County.

For additional info on today’s groundbreaking ceremony, visit http://world wide web.foothillgoldline.org/news/media-sources/.

Concerning the Foothill Gold Line – The Foothill Gold Line Construction Authority (also referred to as the Metro Gold Line Foothill Extension Construction Authority) is definitely an independent transportation planning and construction agency produced in 1998 through the California Condition Legislature to organize, design and make the Metro Gold Line light rail system from Union Station to Montclair. The company completed the very first segment from Union Station to Pasadena in 2003 and also the Pasadena to Azusa segment in 2015 both promptly and under budget. The company started planning the Glendora to Montclair segment in 2003 eco clearing the work under CEQA in 2013. The area of the project within La County (Glendora to Claremont) has been mostly funded by Metro’s Measure M half-cent florida sales tax, in addition to residual Measure R funds in the Pasadena to Azusa segment. The extension to Montclair has been funded by San Bernardino County.

View original quite happy with multimedia:http://world wide web.prnewswire.com/news-releases/foothill-gold-line-light-rail-extension-is-first-measure-m-funded-rail-project-to-break-ground-300565622.html

SOURCE Foothill Gold Line Construction Authority

Related Links

http://world wide web.foothillgoldline.org

Cristóbal, tu ángel en guarda al volante

MARTORELL, España, November 15, 2017 /PRNewswire/ —

El SEAT León más seguro

  • El prototipo desarrollado por SEAT cuenta disadvantage 6 asistentes de seguridad, entre ellos, una caja negra parecida a la de los aviones 
  • Poder controlar la velocidad si tu hijo coge el coche o impedir que arranque si el conductor da positivo dentro del test de alcoholemia, dos de las 19 funciones de Cristóbal 
  • Si la mitad de los coches incorporaran estos sistemas, los accidentes se podrían reducir united nations 40% 

SEAT presenta el concept vehicle León Cristóbal dentro del marco del Smart City Expo, en Barcelona. Testeamos sus principales asistentes disadvantage 1 de los ingenieros que ha participado en su creación, el responsable de Predesarrollo, Patentes e Innovación de SEAT, Stefan Ilijevic:

     (Emblem: http://mma.prnewswire.com/media/604159/SEAT_SA_Emblem.digital )

     (Photo: http://mma.prnewswire.com/media/604164/SEAT_Warning.digital )

     (Photo: http://mma.prnewswire.com/media/604163/SEAT_Camera.digital )

     (Photo: http://mma.prnewswire.com/media/604161/SEAT_Breathalyser.digital )

-Si tu hijo da positivo, el coche no arranca: Disadvantage el asistente ‘Mentor’, los padres pueden limitar la zona por la que el coche puede circular, la velocidad e, incluso, programar el vehículo para que no pueda arrancar dentro del caso de dar positivo dentro del test de alcoholemia, explica Ilijevic.

-La caja negra, del avión al coche: Cuando el vehículo detecta united nations frenazo brusco, una cámara frontal graba los últimos 10 segundos en conducción y se registran todos los indicadores: velocidad, aceleraciones y frenazos.  Este video se envía directamente al teléfono del conductor quien, en caso de accidente, podrá tener una prueba para esclarecer las circunstancias de los hechos.

-Seguir conectados, pero crime distracciones: Alrededor del 36% de los accidentes de tráfico están provocados por distracciones y la primera causa es el uso del teléfono móvil, añade Stefan.  Con el sistema ‘Eyes Track’, el coche percibe si el conductor aparta la vista en carretera. Al detectarlo, una voz lee los mensajes y united nations sistema de respuestas, configuradas, permite contestarlos disadvantage united nations simple gesto.

-A prueba de olvidos: Al apagar el motor del coche, se envía united nations mensaje que recuerda la presencia de pasajeros, ya sean niños o animales, a asientos posteriores. Si se cierra el vehículo dejándolos dentro, el propio coche regula la temperatura interior y envía de nuevo united nations mensaje al conductor. Si aun así éste no respondiera, saltaría la alarma del vehículo.

-Objetivo cero accidentes: La industria del automóvil centra sus esfuerzos en desarrollar nuevos vehículos disadvantage toda la tecnología necesaria para reducir al máximo los accidentes de tráfico. Disadvantage este prototipo, SEAT da united nations paso más allá y es una buena solución para la fase de transición hacia la conducción autónoma y avanzar, así, hacia united nations horizonte de cero accidentes, asegura Stefan.

http://seat-mediacenter.com 

FUENTE SEAT SA

Advicenne Announces Positive 6-Month Extension Study Data from Pivotal Phase III Study of ADV7103 in Children and adults Struggling with distal Kidney Tubular Acidosis (dRTA)

NIMES, France, November 6, 2017 /PRNewswire/ —

Data presented in the American Society of Nephrology (ASN) meeting in New Orleans

– Positive data will form grounds for application seeking market authorization of ADV7103 towards the European Medicines Agency in Europe for dRTA expected in 2018

– Clinicians expect registration from the product for the treatment of dRTA 

Advicenne, a late-stage pharmaceutical company centered on the introduction of pediatric-friendly therapeutics to treat orphan kidney and nerve illnesses, announces positive 6 several weeks follow-up data in the pivotal phase III study (B22CS) assessing ADV7103 in children and adults struggling with dRTA. dTRA is really a disease characterised by an unbalanced pH in your body connected with a lot more disorders for example biochemical impairments that can lead to failure to thrive, rickets/osteomalacia, lithiasis and nephrocalcinosis that can result in kidney failure.

The preliminary outcomes of the 6-month follow-up study assessed the security and effectiveness of two times daily dosing of ADV7103 to treat dRTA both in adult and pediatric patients. The extension study (B22CS) adopted the pivotal phase III trial (B21CS), which demonstrated ADV7103’s capability to restore the primary biological defects observed using the disease, meeting secondary and primary endpoints. The product’s effectiveness, was proven to become maintained at 6 several weeks within this open label extension study, with bloodstream bicarbonate levels above 21 mM – the standard level – in 79% of the sufferers. Individual ADV7103 doses ranged from 1.3 to 7.2 mEq/kg/day.

Overall, patients and/or their parents were very pleased with ADV7103. It was measured utilizing a visual analogue scale (VAS) questionnaire quoting from (no improvement whatsoever) to 100% (very important improvement). The modification of treatment from standard of choose to ADV7103 permitted a typical improvement from the patients’ quality of existence of 80.5% with respect to the age bracket considered the advance ranged from 76 to 98%.

ADV7103 may be the company’s lead product and it has been made to address the condition in adults as well as in children. The condition in youngsters is usually from genetic origin while adults mostly develop dRTA because of autoimmune disease. Positive Phase III recent results for ADV7103 were announced in September this season and shown ADV7103’s capability to normalise the primary biological defects observed using the disease.

Dr Luc-André Granier, Chief executive officer and cofounder of Advicenne, commented, “The 6-month follow-up data presented at ASN are extremely encouraging because they reinforce the obvious benefits our lead product ADV7103 delivers. These data, along with the recent positive phase III results with ADV7103, that have been presented in the European Society for Paediatric Nephrology (ESPN) in September, highlight the potential for ADV7103 to get the very first strategy to dRTA, a kidney orphan disease rich in unmet medical needs.”

Dr Granier added, “Our strong links to key opinion leaders in nephrology, alongside our development expertise and scientific understanding happen to be answer to the effective clinical growth and development of ADV7103. The Advicenne team’s focus continues to be driven by their unwavering dedication to deliver pediatric-friendly therapeutics to patients to treat orphan kidney illnesses that you will find presently no approved treatments.Inch

The poster titled “Safety and effectiveness of ADV7103, a cutting-edge prolonged-release dental alkalising combination product, after 6-several weeks treatment in distal kidney tubular acidosis (dRTA) patients” was presented at ASN on second November 2017. The abstract could be utilized here.

About distal Kidney Tubular Acidosis (dRTA) 

dRTA is really a disease that happens when the kidneys don’t correctly remove acids in the bloodstream in to the urine. Consequently, an excessive amount of acidity remains within the bloodstream which generates an unbalanced pH that can result in failure to thrive and rickets (a disorder that affects bone rise in children) in addition to a selection of additional clinical disorders like a potassium deficiency (hypokalaemia) within the bloodstream serum which alters the part of countless organs and many conspicuously affects the heart. Additionally, a higher power of calcium within the bloodstream and urine (hypercalcemia and hypercalciuria) can result in kidney gemstones and calcinosis that may potentially cause kidney impairment, ultimately resulting in kidney failure. The condition, either genetic (usually occurring during childhood) or acquired because of autoimmune disease, is believed to affect roughly 30,000 patients in Europe and 20,000 in america. Current standard of care are often various unapproved products administered every 4 to 6 hrs to try to re-balance your body’s pH and also to normalise bloodstream potassium level.

About Advicenne 

Advicenne is really a late-stage pharmaceutical company concentrating on the introduction of pediatric-friendly therapeutics to treat orphan kidney and nerve illnesses. The Business’s innovative method is ADV7103 that has proven positive produces a pivotal phase III study in adults and children with distal Kidney Tubular Acidosis (dRTA). ADV7103 may also be coded in another indication to treat Cystinuria, a hereditary kidney tubulopathy and it is expected to initiate a pivotal Phase II/III medical trial in 2018 in Europe.

Additionally to ADV7103, the organization includes a portfolio of clinical and pre-clinical products targeting critical unmet needs in nephrology and neurology together with Key Opinion Leaders.

The Organization started in 2007 in Nimes (France). Since its beginning, the organization has elevated near to €30 million in equity from leading investment capital investors Innobio (Bpifrance), IXO Private Equity Finance, IRDI SORIDEC Gestion, Cemag Invest and MI Care.

More information about Advicenne can be obtained through its website: world wide web.advicenne.com

Disclaimer  

This pr release contains specifics of clinical growth and development of ADV7103.

For more information, please contact:
Advicenne
LA Granier, S Delbaere, J Rachline
[email protected]
+33-()-4-66-05-54-20

Citigate Dewe Rogerson
David Dible, Sylvie Berrebi, Marine Perrier, Laurence Bault, Alexandre Dechaux
[email protected]
+44-()-20-7638-9571 / +33-()-1-53-32-78-87

SOURCE Advicenne

Startup trying to offer WhatsApp for healthcare plans expansion to Nigeria the coming year

Serial healthcare entrepreneur Clinton Phillips is expanding his telehealth business Medici to Nigeria at the beginning of 2018 inside a move meant to improve use of healthcare. Additionally, it follows a $24.two million fundraise by the organization this past year. Phillips, who resided in Gauteng before settling in Austin, Texas, spoken about his plans for the organization inside a phone interview.

Unlike Phillips’ previous healthcare business 2ndMD, another opinion service for complex health conditions, Medici is modeled after WhatsApp however for healthcare. Although patients can initiate connection with doctors by text, physicians can pick for connecting with patients via a video conference component or telephone call.

“A billion people each day use WhatsApp and most of them are doctors. It’s not designed for healthcare, it’s not compliant for healthcare but it’s the easiest way they are fully aware to handle their sufferers.Inches

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Medici intends to onboard 3,000 to five,000 doctors to aid the development to South Africa. Phillips stated the organization is collaborating with medical associations and insurance providers within the African nation, such as the insurer MMI. Surprisingly, Phillips observed the marketplace is much like the U.S. when it comes to private and public insurance. He noted that most South Africans with insurance have high deductible plans.

Nigeria may also anchor Medici’s expansion intentions of the continent — it already has partnerships in Kenya and Nigeria. Additionally, it has designs for Europe and presently comes with an office in Paris staffed by five people.

“We’d love to get at 20 countries within the next 12-18 month. US, Africa & South America are showing lots of potential.”

Provider side of Medici’s chat interface

Their business design enables physicians to make use of its application free of charge in return for some of the revenues or they are able to pay $149 monthly. With what appears as an unusual but practical move, Medici offers free malpractice insurance masking to $a million.

Requested how physicians use Medici, Phillips offered a couple of different examples because of its “power users.” A Miami physician uses it to look after children on Medicaid who’ve limited mobility because she stated it offers helpful understanding of what’s going on inside a patient’s home. Additionally, it has specialists among its users for example an orthopedic surgeon so he is able to tap into patients before their procedure so that as they recover.

Also on Medici’s list are updates to its platform, for example using AI to assist triage consults for that doctors using Medici and transcription to reduce doctors getting to consider notes.

Photo: ronniechua, Getty Images

MedCity ENGAGE, October 23-24 in North Park, concentrates on the most recent strategies and innovations to boost patient engagement, care delivery and company wellness. Use code MCNTAG in order to save $50.

Optical Fiber Pajamas Illuminate to deal with Jaundice in Newborns


Kids born with jaundice need to spend a large amount of amount of time in an illuminated incubator before they are able to metabolize bilirubin hepatically. Nobody likes this, because the child needs to be taken from the parents to invest time in the glass box.

At the Swiss Federal Laboratories for Materials Science (Empa), a brand new illuminated fabric continues to be developed you can use to create baby pajamas that literally blanket the kid see how to avoid. There are technologies that resemble this, like the Biliblanket, but Empa’s technology integrates optical fibers which are no wider than regular thread, directly into traditional clothing fabrics. This will make it easy to use, feel at ease like other baby clothing, and natural for that parents to carry their children during therapy.

Since low power LEDs are utilized because the source of light, small batteries are sufficient to power the material, meaning the pajamas don’t need to be tethered to wall power.

The secret from the technologies are to slightly and precisely bend the optical fibers, from time to time, so that they leak light from the bends. With no bends, the fibers transmit the majority of the light through themselves in one finish to another. Maintaining precisely calculated angles of every optical fiber as it’s woven using the traditional fiber produces a well distributed light pattern.

Study in Biomedical Optics Express: Plenty of fish-yarn weaves: manipulating the light out-coupling of wearable phototherapy devices…

Via: Empa…

Editors

At Medgadget, we set of the most recent medical technology news, interview leaders within the field, and file dispatches from medical occasions from around the globe.

Exactly what do doctors want in the Surgeon General?

Dr. Jerome Adams may be the 20th U.S. Surgeon General.

Since 1871, choices general continues to be acknowledged as the official position when Dr. John Woodworth was hired the very first Supervising Surgeon from the national hospital system. The Marine Hospital was reorganized in to the national hospital system the last year.  On The month of january 4, 1889, Congress renamed the personnel that come with this office because the Commissioned Corps. The Corps started along military lines and initially contained only physicians. Wherever a necessity came about, these were mobilized to fight it.

Just before 1968, choices General was mind from the Public Health Service (PHS).  In 1968, President Lyndon B. Manley delegated down to the PHS to Assistant Secretary of Health insurance and abolished work from the Surgeon General. The positioning of the Surgeon General grew to become what principal deputy from the Assistant Secretary of Health insurance and was accountable for becoming an consultant on medical matters. Later, work from the Surgeon General was reestablished like a staff office inside the office from the Assistant Secretary of Health.

Initially, Dr. John Woodworth was given the job of repairing the Marine Hospital Service, that was inside a condition of disrepair and greatly over-crowded. He could rapidly lift a healthcare facility out of this decrepit condition and, with other people, created the united states Department of Health insurance and Human Services. Work also required part in addressing social problems that impacted health, especially before The First World War. President William Taft hired Rupert Blue to work who concerned themself with the truth that workers didn’t earn enough to consume in a healthy manner. Because the war intensified, he switched his focus to look after wounded veterans and so the Spanish flu if this hit.  Another surgeon general, Hugh S. Cummings, concerned themself using the risks of smoking cigarettes and leaded gasoline.

Possibly among the best-known Surgeon Generals was C. Everett Koop. He offered two terms under Taxation and through the onslaught from the AIDs epidemic. Because his superiors feared AIDs would become the greatest public health catastrophe from the 20th Century, he was made to operate in silence. It wasn’t until 1986 he was permitted to issue a Surgeon General’s statement on AIDS as well as in 1988, a congressional-mandated educational sales brochure around the disease was mailed to each house in america. Koop mentioned, “If ever there is an illness designed for a Surgeon General, it had been AIDS.”

The function from the office from the Surgeon General evolved greatly with time. It’s an office hired through the President of america and also the appointee serves a four-year term. Presently, it’s an office at work from the Assistant Secretary for Health in america Department of Health insurance and Human Services. The expectation from the Surgeon General is the fact that he/she’ll supply the best evidence-based information presently on improving health insurance and to prevent illness and injuries. Choices General is definitely a physician and it is given the job of to be the spokesperson for the federal government on all health-related issues. Furthermore, he/she advises obama and also the secretary of health insurance and human services on all public health manners. Finally, choices general serves on several boards and weighs in on health policy and national initiatives.

What if the new Surgeon General’s top priorities be?
Within the first week of August 2017, Dr. Jerome Adams was confirmed as Surgeon General as nominated by President Jesse Trump. By training, Dr. Adams is definitely an anesthesiologist who also offered because the Indiana condition health commissioner. He promised to tackle the US’s opioid epidemic stating, “The addictive qualities of prescription opioids is really a scourge in the usa and it should be stopped.”

As “The physician from the US” because the office continues to be known as for many years, physicians have strong opinions by what issues choices General should tackle. Inside a recent poll conducted by Platform Q Health,  roughly 45 percent of healthcare providers felt the Surgeon General’s main concern ought to be resourcing addiction recovery and mental health.

Resourcing addiction recovery and mental health
In america presently, greater than 6 from 10 drug overdose deaths involve an opioid. Actually, 91 Americans die each day because of opioids (including both prescription medicine and heroin). The CDC figured that the elevated quantity of opioid-related deaths in the last fifteen years is driven by prescriptions for opioid medications. Inside a New You are able to Occasions data analysis, drug overdose deaths rose 19 percent from 2015 through 2016. Preliminary analysis implies that rates are likely to jump even greater in 2017.

Previous Surgeon General Dr. Vivek Murthy issued a landmark study addressing substance addiction, the very first time in US history. In the 400-page report, he figured that 20.8 million Americans suffer an ingredient use disorder. However, only 10 % of those people get any treatment.

“Substance use disorders represent probably the most pressing public health crises in our time,Inches the report (by Murthy) states. “For way too lengthy, a lot of within our country have viewed addiction like a moral failing. This unfortunate stigma has produced an additional burden of shame which has made individuals with substance use disorders less inclined to come forward and seek help.”

Championing Evidence-Based Patient Education and Fighting Fake Medical News
Roughly 20 % of respondents within the PQ Health poll have the main concern ought to be fighting fake medical news and supplying evidence-based patient information. Presently, more people are searching to the web and social networking to locate medical information. A number of these sites are simply gimmicks to market products or push a particular agenda. There’s no regulation over who gives medical information and it doesn’t need to end up being evidence-based. Clearly, some standards have to be set to make sure people are being able to access probably the most up-to-date and accurate health information.

Promoting Antibiotic Stewardship
Roughly 18 percent of respondents felt promoting antibiotics ought to be a high priority from the office from the Surgeon General. The CDC reported that each year in america, roughly two million people become have contracted a bacteria that’s resistant against antibiotics. Greater than 23,000 individuals will die of those infections. And others die from problems that were complicated by antibiotic-resistant infections.

Many experts attribute an upswing of antibiotic potential to deal with the misuse and overuse of antibiotics. The rise of antibiotic resistance isn’t just within the U.S. however a global phenomenon that’s threatening our capability to fight microbial infections. Using antibiotics first began in 1928 using the discovery of Penicillin by Mister Alexander Fleming. Countless lives happen to be saved through their use ever since then. Regrettably, we view antibiotic potential to deal with virtually every known antibiotic. Actually, Fleming first elevated the warning concerning the overuse of antibiotics in 1945.

Antibiotics are actually a restricted resource, you will find presently less effective antibiotics readily available for certain health-care-connected infections than in the last decade, and the specter of antibiotic resistance is real.”  Boris D. Lushniak, MD, Miles per hour RADM, U.S. Public Health Service Acting Surgeon General

Reemphasizing Vaccinations
Roughly 17 % from the poll respondents felt that reemphasizing vaccines ought to be the main concern. In today’s world, we view the results from the anti-vaxxer propaganda and just how distributing myths/fake news can lead to harm when children don’t get the vaccines they require. Our previous Surgeon General Murthy placed significant focus on stopping illnesses and greatly encouraged individuals to receive vaccines. Actually, he met with Sesame Street icon, Elmo in March 2015 and filmed an open safety announcement around the safety and effectiveness of vaccines. He mentioned the web would be a tool that, while proficient at amplifying reliable information, also amplifies unsound information too, which makes it particularly challenging. Obviously, this problem is directly consistent with championing evidence-based patient education and fighting fake medical news.

The United States, along with the world, has become facing public health issues we have never faced before. We’ve technology that disseminates information rapidly and vastly. We currently be capable of achieve around the world to assist others. Contrarily, any mistakes could be a plague to the healthiness of others.

Choices General is within a distinctive position to advise leaders and also the public alike concerning the most pressing health problems in our occasions. While you can come with an opinion regarding the most threatening, possibly they all are essential and national strategies have to be in position to deal with each area within the lengthy term.

Veterans Matters Federal Supply Service Supplier Presently Has a Small-Enema Readily available for Children

PHOENIX, March. 20, 2017 /PRNewswire/ — Alliance Labs, a Phoenix, Arizona based pharmaceutical wholesaler / retailer, is very happy to announce the first-of-this category formulation, DocuSol® Kids, how to be provided in popular Texas retail grocer, H-E-B. DocuSol® Kids includes a delivered dose of 100mg docusate sodium inside a polyethylene glycol base. The docusate sodium functions like a softener by preparing the stool to readily mix with watery fluids. The elevated mass of stool promotes a bowel evacuation by stimulating nerve endings within the bowel lining and initiating peristalsis. It doesn’t only soften and release the stool however it initiates an ordinary stimulus. DocuSol® Kids offers the most basic replicated bowel movement of bowel maintenance systems currently available, having a bowel movement occurring by 50 percent-fifteen minutes, as much as 72 minutes quicker than other leading constipation products available on the market. DocuSol Kids® is made for general constipation relief for adolescents 2-12 years old.

Studies have shown kids with chronic constipation possess a worse quality of existence than individuals with increased serious health conditions like inflammatory bowel disease, and based on a current European study printed within the Journal of Pediatrics, a quarter of children struggling with this problem continues signs and symptoms as adults. “We’re very happy to bring this unique product towards the children’s pharmaceutical market, and excited for that patrons of H-E-B along with other retailers to possess immediate access for this product. Docusol Kids is definitely an enormous help to children struggling with constipation and also the parents and guardians taking proper care of them,” stated Attila Juhasz, Alliance Labs National Brand Manager.

About Alliance Labs LLC – Alliance Labs provides the greatest quality incontinence products to the us government, national pharmaceutical wholesalers, retailers and medical service providers across the nation. Alliance Labs, may be the distributor from the Docusol® and Enemeez® products. Like a staff, we research and pursue products made to enhance the lives of the sufferers we serve.

MEDIA CONTACTS:
Attila Juhasz
National Brand Manager
Alliance Labs LLC
602-276-3434
[email protected]

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SOURCE Alliance Labs LLC

Automatic-Aided Surgery – Current Challenges and Future Directions: Interview with Dr. Mona Orady

Over the past decade . 5, automatic-aided surgery has brought to smaller sized scars, less discomfort, and faster recoveries for patients. Concurrently, surgeons by using this technology have taken advantage of having the ability to perform surgeries inside a much more comfortable position, whilst experiencing greater visualization that has been enhanced precision. Wonderful these benefits, automatic-aided surgeries have become more and more common worldwide, especially in the U . s . States, where greater than 67 percent famous Intuitive Surgical‘s da Vinci robots are set up. Furthermore, just yesterday we covered the Food and drug administration clearance from the Senhance surgical automatic system from TransEnterix, the very first true competitor towards the da Vinci.  (Note: The photos from the automatic system in the following paragraphs have the Senhance, and therefore are thanks to TransEnterix.)

However, just like any disruptive technology, it faces some skepticism and challenges. We at Medgadget were in the MIS WEEK in Bay Area earlier this year and sitting lower with Dr. Mona Orady, Non-invasive Gynecologic Surgeon, Director of Automatic Surgery Services, St. Francis Memorial Hospital, Dignity Health Medical Group, to speak much more about the obstacles facing automatic-aided surgery and it is future.

Medgadget, Kenan Raddawi, M.D: Prior to getting began, inform us more details on your job in automatic-aided surgery and the reason why you made the decision to enter seo.

Dr. Mona Orady: I’ve been doing automatic surgery because the finish of 2007, just 2 yrs following the Food and drug administration approved using automatic aided surgery in gynecological surgery.

I recall the very first patient I’d after i was beginning to include automatic-aided surgery into my non-invasive surgery tool package. She would be a single mom of six children, with three jobs, along with a huge uterus because of fibroids. My first question to her was why have you wait such a long time to find treatment? Why didn’t you will find the surgery earlier? She responded, “Nobody explained which i might have the surgery refrained from taking six or even more days off work. Basically take six days off work, I will lose my job after which the house, and my children is going to be in the pub.Inches That patient is among individuals who helped me be a automatic surgeon, because I saw that automatic surgery could push the boundaries of laparoscopy and non-invasive surgery to incorporate patients who otherwise will not have a non-invasive option.

In automatic surgery, you’ve elevated vision, more precision, and elevated skill. Therefore, I saw the possibility to complete more difficult surgeries utilizing a robot. In those days, I did not be aware of degree that individuals limits might be pressed, however, greater than a 1000 complex surgeries later, I’ve discovered that the majority patients, regardless of how complex, will have a non-invasive surgical option.

Medgadget: What is your opinion would be the primary obstacles and challenges facing the adoption of automatic-aided surgery?

Dr. Orady: The greatest obstacles towards the adoption of automatic-aided surgery happen to be a couple of things: first, the price, and 2nd, working out. You’re speaking to somebody who has been very associated with residency training and education. I helped get the curriculum for residents training in the Cleveland Clinic. I implemented it, and that i helped train the residents within the enter in non-invasive surgery using a mix of didactic teaching, laboratory simulation, and on the job training.

The problem with automatic-aided surgery training is the fact that there’s a real dichotomy. You do not just learn ways to use the instrument, however, you should also learn to carry out the surgery. Whenever we train during residency, and almost in any schools, everyone concentrates on manual skill and becoming to understand the tool. However, just like important, and much more important, may be the knowledge of surgery being an art. If you’re teaching someone how you can paint, you do not provide him a brush and simply tell him ways to use the paint and just what colors to dip in. You need to educate him the idea of 3D depth perception, what lies beneath the surface, the sunlight, shadows, etcetera. It’s the same manner with surgery. We ought to educate the concepts of hemostasis, dissection techniques, and the way to avoid traumatizing tissue, etc. It’s an unfortunate reality that in many Obstetrics and Gynecology residencies, there’s a lot to understand in 4 years – obstetrics, gynecology, primary care, office procedures, automatic surgery – and frequently, one thing that will get neglected is surgical techniques. Because of this , the advent and interest in Non-invasive Surgical Fellowships is growing, and the requirement for the niche to separate as numerous others did, has become more apparent.

Medgadget: What are the technical/logistic factors that restrict the performance of automatic-aided surgery?

Dr. Orady: Let’s first discuss what many people working in the area of automatic surgery usually explain as missing or restricting factors, after which, discuss things i personally want after i execute a automatic-aided surgery. Lots of surgeons explain the truth that in automatic aided surgery, it’s not necessary haptic feedback. You lose a feeling of touch. In my experience, that has not been a large issue because after you have done this most cases, it become super easy to get the capability to feel with an alternate feeling of vision, so known as “visual hepatics”, and so i don’t take into account that being an issue. The publication of the size the robot and seeking to pier it’s been improved with newer models. A few of the newer surgical robots which are being developed are smaller sized, slimmer, and outfitted with longer arms to achieve the surgery site while allowing employees to gain access to the individual within an simpler way. When it comes to energy, In my opinion all automatic companies need to pay attention to their energy application. I helped write articles about the way forward for energy, and for me, while sticking with just traditional monopolar and bipolar energy is ok. But, automatic companies really should enter into the advanced bipolar energy, I’m not speaking concerning the sealing, cutting techniques, however i am speaking about advanced impedance recognition, having a pulsed waveform, and modifying the kind and creation of energy towards the tissue reaction. We view that Intuitive Surgical had the PK energy within their Si system and required them back their new Xi system. I have faith that is really a mistake, once we should not go backwards and really should always attempt to move towards using more complex energy for the patients.

Medgadget: What’s the one factor you want you’d any time you sit lower at the da Vinci console?

Dr. Orady: Undoubtedly If only for smaller sized instruments. Eight millimeters continues to be pretty big, especially since i have perform Microlaparoscopical and Minilaparoscopical surgery. I personally use 3 millimeters instruments in traditional laparoscopic procedures. Jumping from three millimeters – almost a scarless cut – to eight millimeters cut is exactly what sometimes steers me more lower the laparoscopy route as opposed to the automatic-aided route. The 2nd factor that If only I’d is really a dedicated and trained team. A passionate automatic team is among the most significant things for efficiency inside a automatic-aided procedure. The robot differs from other traditional surgical treatments. It’s a pc-based product, there’s lots of troubleshooting happening, and you need to be capable of working through and connect error messages efficiently. Therefore, to optimize the part from the robot, you’ll need somebody that is actually savvy in modifying things perfectly and rapidly.

Medgadget: Intuitive Surgical has already established without any competitors during the last decade. Do you consider this can change in the near future?

Dr. Orady: It certainly can change. It can’t stay like this forever. The da Vinci robot has been available since 1999, so almost twenty years. New automatic companies happen to be focusing on their robots for maybe ten years or even more although, not one of them happen to be Food and drug administration approved yet however, many are extremely close. [Note: this interview was conducted before the Food and drug administration clearance of Senhance from TransEnterix] Actually, another product is presently getting used in Europe and could be Food and drug administration approved over the following couple of days to several weeks. Now you ask ,, can they get caught up? Maybe, and many likely, most likely. Intuitive Surgical hasn’t really innovated much within the last ten years. They almost stored everything exactly the same, as well as when i pointed out before, go backwards sometimes, like removing advanced bipolar energy using their new Xi system. Also, Intuitive Surgical is focusing more about moving towards single port surgery rather of concentrating on smaller sized instruments. For me, this might not always be to right direction, owing to single port surgery, you finish track of a larger, more painful cut, and research has proven that. In my opinion future automatic firms that will concentrate on smaller sized incisions, while keeping the truth and vision, are the type which will succeed later on.

Medgadget: What is the way forward for automatic surgery? Do you consider Artificial Intelligence (AI) can lead to automatic-aided surgery? Shall we be moving towards more automation during these kinds of surgeries?

Dr. Orady: In my opinion tissue is extremely dynamic. You will find a lot of variables – the effectiveness of the tissue, the feel, and just how it stretches and reacts to tension and is very variable person to person. It’s an excessive amount of data to input right now to think that AI can completely dominate. Artificial intelligence will certainly help guide to our hands and eyes when we’re performing the process using overlapped imaging or any other recognition methods.

I have faith that in very specific procedures, like placing stents or perhaps in valvuloplasty, where it’s a fairly straightforward procedure with minimal steps, we may see more automation utilizing artificial intelligence. However, when it comes to intra-abdominal pelvic surgery, the variability and dynamic variation in anatomy make these kinds of surgical treatments really complicated so that you can automate. It is not easy enough to educate human brains how to sit in variables in anatomy and also the dynamic facets of tissue reaction and also to adjust and vary technique for everybody situation because the situation progresses. Thus, outdoors of utilizing AI to assist locate anatomy or educate people how to sit in the dynamic movement from the tissue, it might be hard to depend onto it to really carry out the procedures. I’m not going to say never, however i believe the quantity of investment you need to place in will far exceed the price of purchasing training good surgeons and teaching them ways to use the information which we are able to obtain using advanced imaging and advanced energy to merely perform better, better, and fewer invasive surgery.

Also, In my opinion what’s going to happen later on in surgical treatment is consolidation. We can’t educate 100 1000 physicians to do countless procedures. I believe everyone will probably be great in a couple of things and merely repeat individuals procedures. Repetition is essential. For surgeons making them repeat exactly the same surgery again and again, they will improve. Should you perform a hysterectomy monthly versus ten per month, the advance rate is going to be exponential. It’s just like a pianist who practices a bit of music daily versus monthly.

Yes, robots will end up more automated in performing some things, like real-time imaging. But, will a surgical procedure be practiced completely by AI with no surgeon? I believe at this time we’re too much from this.

Flashback: The Possible Future of Surgical Robotics: Interview with Chief executive officer of TransEnterix… TransEnterix Will get Food and drug administration Clearance for Senhance Surgical Robot…